97318-75-7Relevant academic research and scientific papers
Visible-light-mediated arylation of: Ortho -hydroxyarylenaminones: Direct access to isoflavones
Mkrtchyan, Satenik,Iaroshenko, Viktor O.
, p. 2606 - 2609 (2020)
In this work we highlight two new methods for the synthesis of isoflavones through consecutive domino arylation of ortho-hydroxyarylenaminones with in situ photogenerated aryl radicals. As precursors for aryl radicals we used aryl onium reagents such as diazonium and diaryliodonium salts. Notably, the photo-Meerwein arylation by aryl diazonium tetrafluoroborates demonstrated high efficiency in terms of yields and can be considered as a method of choice for the straightforward assembly of 3-aryl-substituted chromones. Ultimately, 26 compounds were prepared in good to excellent yields using the developed synthetic protocols.
