97336-47-5

Upstream product

• 143395-28-2 (1R,5R)-5-hydroxymethyl-2-cyclopenten-1-ol 
• 188118-68-5 Acetic acid (1R,2R,3S,4R)-4-(6-benzoylamino-purin-9-yl)-2,3-dihydroxy-cyclopentylmethyl ester 
• 188118-64-1 Acetic acid (1S,4R)-4-(6-benzoylamino-purin-9-yl)-cyclopent-2-enylmethyl ester 
• 178456-34-3 (1R,2R)-2-acetoxy-1-(acetoxymethyl)-3-cyclopentene 
• 160154-62-1 (S)-2-Acetoxy-propionic acid (3S,3aS,6aR)-2-oxo-3,3a,4,6a-tetrahydro-2H-cyclopenta[b]furan-3-yl ester 
• 148473-12-5 (1R,5S,1'S)-5-(1',2'-Dihydroxyethyl)cyclopent-2-en-1-ol 
• 216441-13-3 (1S,2R)-2-Hydroxy-cyclopent-3-enecarbaldehyde 
• 40615-36-9 4,4'-dimethoxytrityl chloride 
• 19186-33-5 aristeromycin 

Downstream Products

• 97336-49-7 (1S,2R,3R,5R)-5-(6-Amino-purin-9-yl)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(tert-butyl-dimethyl-silanyloxy)-cyclopentanol 
• 97336-48-6 (1R,2S,3R,5R)-3-(6-Amino-purin-9-yl)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(tert-butyl-dimethyl-silanyloxy)-cyclopentanol 
• 97336-50-0 9-[(1R,2S,3R,4R)-4-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-cyclopentyl]-9H-purin-6-ylamine 

Relevant academic research and scientific papers

Synthesis and incorporation of carbocyclic nucleosides into a hammerhead ribozyme domain-RNase resistance and catalytic activity

A hammerhead ribozyme domain incorporating (-)-carbodine 8a and (-)-aristeromycin 8b at selected positions, manifests increased RNase resistance and exhibits significant catalytic activity.

Replacement of the Ribofuranose Oxygen of 2-5A Derivatives by Methylene: Synthesis of an Aristeromycin Analogue of 2-5A Core 5'-Monophosphate (5'-O-Phosphoryladenylyl)(2'->5')adenylyl(2'->5')adenosine

The ribofuranose oxygens of the the three adenosine residues of the 5'-monophosphate of the 2-5A core 5')adenylyl(2'->5')adenosine> were replaced by methylenes through the synthesis of an aristeromycin 9-(1R,2S,3R,4R)-2,3-dihydroxy-4-(hydr