97408-38-3Relevant academic research and scientific papers
Direct synthesis of imines from alcohols and amines with liberation of H2
Gnanaprakasam, Boopathy,Zhang, Jing,Milstein, David
supporting information; experimental part, p. 1468 - 1471 (2010/05/02)
"Chemical equation presented" A clean sweep: Aryl and aliphatic mines can be synthesized directly and efficiently from alcohols and amines under mild, neutral conditions with the liberation of only molecular hydrogen and water (see scheme; R=isopropyl, tert-butyl). This general, environmentally benign reaction is catalyzed by a de-aromatized ruthenium PNP pincer complex (0.2 mol%), and can proceed in toluene under an inert atmosphere or under air.
Facile synthesis and in vitro properties of 1-alkyl- and 1-alkyl-N-propargyl-1,2,3,4-tetrahydroisoquinoline derivatives on PC12 cells
Kitabatake, Michikazu,Nagai, Junko,Abe, Kenji,Tsuchiya, Yukihiro,Ogawa, Keita,Yokoyama, Takashi,Mohri, Kunihiko,Taguchi, Kyoji,Horiguchi, Yoshie
experimental part, p. 4034 - 4043 (2009/12/04)
The synthesis of several 1-alkyl-1,2,3,4-tetrahydroisoquinolines, which may play an important role in Parkinson's disease, has been achieved by modified Pictet-Spengler cyclization of the formyliminium ion. The direct cytotoxicity and preventative effects
