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Tyr-D-Ala-Phe-Gly-NH2, also known as Tyrosine-D-Alanine-Phenylalanine-Glycine amide, is a synthetic pentapeptide consisting of five amino acids: Tyrosine, D-Alanine, Phenylalanine, Glycine, and an amide group. This peptide is structurally similar to naturally occurring peptides, such as enkephalins, which are endogenous opioids involved in pain modulation and neurotransmission. Tyr-D-Ala-Phe-Gly-NH2 has been studied for its potential therapeutic applications, particularly in the development of analgesic drugs, due to its ability to bind to opioid receptors in the central nervous system. However, it is important to note that the peptide's activity and efficacy may vary depending on its specific sequence and stereochemistry, as well as its interactions with various receptors and biological systems.

97412-74-3

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97412-74-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 97412-74-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,4,1 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 97412-74:
(7*9)+(6*7)+(5*4)+(4*1)+(3*2)+(2*7)+(1*4)=153
153 % 10 = 3
So 97412-74-3 is a valid CAS Registry Number.

97412-74-3Upstream product

97412-74-3Downstream Products

97412-74-3Relevant academic research and scientific papers

FIRST DIRECT FLUORINATION OF TYROSINE-CONTAINING BIOLOGICALLY ACTIVE PEPTIDES

Hebel, D.,Kirk, K.L.,Cohen, L.A.,Labroo, V.M.

, p. 619 - 622 (1990)

Using acetyl hypofluorite a regiospecific electrophilic fluorination of the tyrosine ring of the N-terminal tetrapeptide amide (Tyr-D-Ala-Phe-Gly-NH2) sequence of the opiate peptide dermorphin has been achieved in good yields.

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