97463-09-7Relevant academic research and scientific papers
VINIL-COPPER DERIVATIVES XII : STEREOSPECIFIC SYNTHESIS OF ALLYLIC AMINES BY AMINOMETHYLATION OF ORGANOCOPPER REAGENTS
Germon, C.,Alexakis, A.,Normant, J. F.
, p. 3763 - 3766 (1980)
The carbocupration or hydroalumination of alkynes followed by aminomethylation yields allylic amines.The stereochemical integrity of the alkenyl moiety is completely retained in both cases.
Rhodium-Catalyzed Asymmetric Synthesis of β-Branched Amides
Wu, Zhao,Laffoon, Joshua D.,Nguyen, Trang T.,McAlpin, Jacob D.,Hull, Kami L.
supporting information, p. 1371 - 1375 (2017/01/24)
A general asymmetric route for the one-step synthesis of chiral β-branched amides is reported through the highly enantioselective isomerization of allylamines, followed by enamine exchange, and subsequent oxidation. The enamine exchange allows for a rapid and modular synthesis of various amides, including challenging β-diaryl and β-cyclic.
