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(6R)-6,7,8,9-Tetrahydro-6β,7β-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione is a naturally occurring chemical compound with the molecular formula C18H14O5. It is derived from the genus of fungi Aspergillus and Penicillium and is known for its potent biological activities. (6R)-6,7,8,9-Tetrahydro-6β,7β-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione exhibits a unique chemical structure and has demonstrated antifungal, antibacterial, anti-inflammatory, and anticancer properties, making it a promising candidate for further research and potential drug development.

97465-70-8

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97465-70-8 Usage

Uses

Used in Pharmaceutical Industry:
(6R)-6,7,8,9-Tetrahydro-6β,7β-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione is used as a pharmaceutical agent for its antifungal and antibacterial properties. Its ability to inhibit the growth of various fungi and bacteria makes it a potential candidate for the development of new antimicrobial drugs to combat drug-resistant infections.
Used in Anti-inflammatory Applications:
(6R)-6,7,8,9-Tetrahydro-6β,7β-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione is used as an anti-inflammatory agent due to its ability to reduce inflammation in various conditions. Its anti-inflammatory properties can be harnessed to develop new treatments for inflammatory diseases, such as arthritis, asthma, and inflammatory bowel diseases.
Used in Anticancer Applications:
(6R)-6,7,8,9-Tetrahydro-6β,7β-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione is used as an anticancer agent for its potential to inhibit the growth and proliferation of cancer cells. Its anticancer activities have been demonstrated in various studies, making it a promising candidate for the development of new cancer therapies.
Used in Drug Delivery Systems:
To enhance the bioavailability and therapeutic outcomes of (6R)-6,7,8,9-Tetrahydro-6β,7β-dihydroxy-1,6-dimethylphenanthro[1,2-b]furan-10,11-dione, novel drug delivery systems can be developed. These systems, such as organic and metallic nanoparticles, can improve the compound's delivery to target tissues, increasing its efficacy and reducing potential side effects.

Check Digit Verification of cas no

The CAS Registry Mumber 97465-70-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,4,6 and 5 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 97465-70:
(7*9)+(6*7)+(5*4)+(4*6)+(3*5)+(2*7)+(1*0)=178
178 % 10 = 8
So 97465-70-8 is a valid CAS Registry Number.

97465-70-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name Phenanthro[1,2-b]furan-10,11-dione, 6,7,8,9-tetrahydro-6,7-dihydroxy-1,6-dimethyl-, (6R,7S)-

1.2 Other means of identification

Product number -
Other names Tanshindiol B

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:97465-70-8 SDS

97465-70-8Downstream Products

97465-70-8Relevant academic research and scientific papers

Total synthesis of (±)-tanshinol B, tanshinone I, and (±)-tanshindiol B and C

Wang, Fan,Yang, Hong,Yu, Shujuan,Xue, Yu,Fan, Zhoulong,Liang, Gaolin,Geng, Meiyu,Zhang, Ao,Ding, Chunyong

, p. 3376 - 3381 (2018/05/23)

A concise and efficient approach was established for the divergent total synthesis of (±)-tanshindiol B and C and tanshinone I from a ubiquitous ene intermediate in 1-2 steps. This critical intermediate was derived from (±)-tanshinol B, which was synthesized in 50% overall yield over 3 steps using an ultrasound-promoted cycloaddition as a key step. Compared to a previously reported strategy, our approach is more step-economic, thus greatly improving the synthetic efficiency. The bioactivity evaluation indicates that the diol stereochemistry of the tanshidiols has an impact on the EZH2 inhibitory activity.

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