97477-81-1 Usage
Uses
Used in Pharmaceutical Industry:
3-(5-CHLORO-2-BENZOXAZOLYL)-4-CYANO-7-HYDROXYCOUMARIN is used as a potential therapeutic agent for various applications due to its potential biological activities. Its anti-inflammatory properties make it a candidate for the treatment of inflammatory diseases, while its anti-cancer properties suggest its potential use in oncology for the development of novel cancer therapies.
Used in Antimicrobial Applications:
In the field of antimicrobial research, 3-(5-CHLORO-2-BENZOXAZOLYL)-4-CYANO-7-HYDROXYCOUMARIN is used as a potential antimicrobial agent. Its ability to target and inhibit the growth of microorganisms could contribute to the development of new antibiotics or antifungal agents, addressing the growing issue of antibiotic resistance.
Used in Research and Development:
3-(5-CHLORO-2-BENZOXAZOLYL)-4-CYANO-7-HYDROXYCOUMARIN is utilized in scientific research and development for the exploration of its pharmacological properties. Its unique structure provides a basis for studying its interactions with biological systems, which could lead to the discovery of new mechanisms of action and potential applications in medicine.
Check Digit Verification of cas no
The CAS Registry Mumber 97477-81-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,4,7 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 97477-81:
(7*9)+(6*7)+(5*4)+(4*7)+(3*7)+(2*8)+(1*1)=191
191 % 10 = 1
So 97477-81-1 is a valid CAS Registry Number.
97477-81-1Relevant academic research and scientific papers
Wolfbeis, Otto S.,Koller, Ernst,Hochmuth, Petra
, p. 731 - 734 (1985)
Synthesis, absorption and fluorescence spectra as well as pKa values of 7-hydroxycoumarins with electron-withdrawing substituents in positions 3 are described.Introduction of 4-cyano group is achieved by oxidative cyanation of coumarins using potassium cyanide and elemental bromine. 7-Hydroxycoumarins without a 4-cyano group are useful indicators for measuring physiological pH values due to their intense fluorescences, longwave absorptions and emissions, as well as pKa values of around 7.The presence of a 4-cyano group gives rise to a dramatic longwave shift in absorption (30-40 nm in methanol) and emission (55-80 nm).In water solution, the fluorescence maxima are at around 570-600 nm, with excitation maxima between 410 and 510 nm, depending on whether the phenol or phenolate species is excited.For all coumarins under investigation, fluorescence is from the anion form even in the pH 2-7 range.This phenomenon is interpreted in terms of excited state dissociation according to the Foerster model.The interpretation is corroborated by calculations of the excited state pKa values, which show them to be lower by 4.5-6.4 units than those of the ground state.
