97482-04-7

Basic information

• Product Name: 3,6-Dimethyl-2-methylsulfanyl-3,4,5,6-tetrahydro-pyrimidin-4-ol; hydriodide
• CAS NO: 97482-04-7
• Molecular Weight: 302.179
• Mol File: 97482-04-7.mol

Chemical Properties

• CAS DataBase Reference: 3,6-Dimethyl-2-methylsulfanyl-3,4,5,6-tetrahydro-pyrimidin-4-ol; hydriodide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,6-Dimethyl-2-methylsulfanyl-3,4,5,6-tetrahydro-pyrimidin-4-ol; hydriodide(97482-04-7)
• EPA Substance Registry System: 3,6-Dimethyl-2-methylsulfanyl-3,4,5,6-tetrahydro-pyrimidin-4-ol; hydriodide(97482-04-7)

Safety Data

• Hazardous Substances Data: 97482-04-7(Hazardous Substances Data)

Upstream product

• 27406-58-2 3,6-dimethyl-4-hydroxyhexahydropyrimidine-2-thione 
• 74-88-4 methyl iodide 

Relevant articles and documents

REACTIVITY AND STEREOCHEMICAL STRUCTURE OF 4-HYDROXY- AND 4-ALKOXYHEXAHYDROPYRIMIDINE-2-THIONES

Substituted 4-hydroxyhexahydropyrimidine-2-thiones were obtained by the reaction of β-isothiocyanatoaldehydes with ammonia or methylamine.When heated with alcohols in the presence of p-toluenesulfonic acid, the synthesized compounds gave the corresponding 4-alkoxyhexahydropyrimidine-2-thiones, which were converted into other 4-alkoxy derivatives by the action of the respective alcohols and were hydrolyzed to the initial 4-hydroxyhexahydropyrimidine-2-thiones by the action of an aqueous solution of oxalic acid or potassium hydroxide.The reaction of the4-hydroxyhexahydropyrimidine-2-thiones with methyl iodide led to the formation of 2-methylthio-4-hydroxy-3,4,5,6-tetrahydropyrimidine hydroiodides.It was shown by PMR spectroscopy that the stereoisomers in which the hydroxyl (or alkoxyl) group has the axial orientation are thermodynamically more stable.