97492-34-7Relevant academic research and scientific papers
Computational Mechanistic Study on the Nickel-Catalyzed C-H/N-H Oxidative Annulation of Aromatic Amides with Alkynes: The Role of the Nickel (0) Ate Complex
Yamazaki, Ken,Obata, Atsushi,Sasagawa, Akane,Ano, Yusuke,Chatani, Naoto
supporting information, p. 248 - 255 (2019/02/01)
Density functional theory (DFT) was used to unveil intimate mechanistic insights on the monodentate-chelation system that is used in the Ni-catalyzed C-H/N-H oxidative annulation of aromatic amides with alkynes, a reaction that was originally reported by
Stable and Reusable Binaphthyl-Supported Palladium Catalyst for Aminocarbonylation of Aryl Iodides
Sharma, Nidhi,Sekar, Govindasamy
supporting information, p. 314 - 320 (2016/02/14)
A binaphthyl-supported Pd nanoparticles (Pd-BNP)-catalyzed aminocarbonylation of aryl iodides in the presence of carbon monoxide and amines for the synthesis of amides has been developed. This methodology provides an efficient route for the synthesis of a COX-2 enzyme inhibitor having anti-inflammatory activity.
Synthesis, antileishmanial activity and structure-activity relationship of 1-N-X-phenyl-3-N′-Y-phenyl-benzamidines
Rodrigues-Santos, Cláudio Eduardo,Leon, Leonor L.,Bortoluzzi, Adailton J.,Canto-Cavalheiro, Marilene Marcuzzo,Machado, Gérzia C.,Echevarria, Aurea
, p. 166 - 174 (2013/10/01)
Two series of N,N′-diphenyl-benzamidines were synthesized as part of a study to search potential new drugs with antileishmanial activity. These compounds were obtained by anilides in PCl5 halogenation reaction with generation in situ of the cor
Synthesis and biological relationships of 3′,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents
Lai, Ya-Yun,Huang, Li-Jiau,Lee, Kuo-Hsiung,Xiao, Zhiyan,Bastow, Kenneth F.,Yamori, Takao,Kuo, Sheng-Chu
, p. 265 - 275 (2007/10/03)
As part of a continuing search for potential anticancer drug candidates in the 2-phenyl-4-quinolone series, 3′,6-substituted 2-phenyl-4-quinolone-3- carboxylic acid derivatives and their salts were synthesized and evaluated. Preliminary screening showed t
Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents
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Page/Page column 6, (2008/06/13)
Substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives and their salts were synthesized. The results of preliminary screening revealed that these compounds are potent in killing solid tumor cancers.
