97501-13-8Relevant academic research and scientific papers
A versatile entry into the synthesis of α-(monofluoromethyl) amino acids : Preparation of α-(monofluoromethyl) serine and (E)-dehydro-α-(monofluoromethyl) ornithine
Van Hijfte, Luc,Heydt, Veronique,Kolb, Michael
, p. 4793 - 4796 (2007/10/02)
A new entry to the synthesis of α-(monofluoromethyl) amino acids is described. The synthesis is based on a Strecker reaction on an α-(monofluoromethyl) ketone. As an example, α-(monofluoromethyl) serine was synthesized and used as starting material for a new synthesis of (E)-dehydro-α-(monoflouromethyl) ornithine.
Fluorinated pentene diamine derivatives
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, (2008/06/13)
Fluorinated alkenylene diamine compounds are inhibitors of ornithine decarboxylase enzyme in vivo and have the following formula: STR1 wherein: Ra represents hydrogen or R2, where R2 is as defined below; Rb represents hydrogen or, when Ra is hydrogen, R2, where R2 is as defined below; Rc represents hydrogen or --COR3, where R3 is as defined below; R1 represents hydrogen or C1 --C6 alkyl; each R2, independently, represents C2 -C5 alkylcarbonyl, phenylcarbonyl, phenyl-(C1 -C4 alkyl) carbonyl, or an aminocarboxylic acid residue derived by removal of an hydroxy group from a carboxy moiety of an L-aminocarboxylic acid; R3 represents hydroxy, or, when Ra and Rb are both hydrogen, C1 -C8 alkoxy, --NR4 R5, where R4 and R5 are as defined below, or an aminocarboxylic acid residue derived by removal of an hydrogen atom from the amino moiety of an L-aminocarboxylic acid; R4 and R5, independently, represent hydrogen or C1 -C4 alkyl; and p represents 1 or 2.
Method of inhibiting the growth of protozoa
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, (2008/06/13)
α-Substituted amines and α-substituted-α-amino acids are described which are useful in inhibiting the growth of protozoa in animals.
Method of inhibiting algae
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, (2008/06/13)
α-Substituted amines and α-substituted-α-amino acids are described which are useful in controlling the growth of algae.
