97514-92-6

Upstream product

• 102906-22-9 (6E,10E,12E)-(5S,14S,15R)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid methyl ester 
• 102906-19-4 (6E,10E,12E)-(5S,14S,15R)-5,14,15-Trihydroxy-icosa-6,10,12-trien-8-ynoic acid 
• 90108-28-4 (5S)-5-hydroxy-hept-6-ynoic acid, methyl ester 
• 97514-91-5 (6E,10E,12E)-(5S,14S,15R)-5,14,15-Tris-(tert-butyl-dimethyl-silanyloxy)-icosa-6,10,12-trien-8-ynoic acid methyl ester 
• 97514-89-1 (3E,5E)-(7S,8R)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne 
• 97514-89-1 (3E,5Z)-(7S,8R)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-1-trimethylsilanyl-trideca-3,5-dien-1-yne 
• 97514-96-0 (3E,5E)-(7S,8R)-7,8-Bis-(tert-butyl-dimethyl-silanyloxy)-trideca-3,5-dien-1-yne 
• 106031-56-5 2,2-Dimethyl-propionic acid (2S,3R)-2,3-bis-(tert-butyl-dimethyl-silanyloxy)-octyl ester 
• 106031-60-1 (S)-6-((1E,5E,7E)-(9S,10R)-9,10-Dihydroxy-pentadeca-1,5,7-trien-3-ynyl)-tetrahydro-pyran-2-one 
• 127505-69-5 (2S,3S)-2,3-bis(tert.butyldimethylsiloxy) octanal 
• 91842-16-9 (E)-(S)-7-Bromo-5-(tert-butyl-dimethyl-silanyloxy)-hept-6-enoic acid methyl ester 
• 91842-15-8 (-)-(5S)-methyl 5-<(tert-butyldimethylsilyl)oxy>-6-heptynoate 
• 93398-58-4 (2S,3R)-2,3-Bis-(tert-butyl-dimethyl-silanyloxy)-octan-1-ol 
• 106031-55-4 2,2-Dimethyl-propionic acid (2S,3R)-2,3-dihydroxy-octyl ester 

Relevant academic research and scientific papers

Stereocontrolled Total Synthesis of Lipoxins B

A stereocontrolled total synthesis of six lipoxin B isomers are described.The flexible and stereoselective strategy involves Sharpless asymmetric epoxidation and pinylborane asymmetric reduction to secure the three hydroxyl-bearing stereocenters and a Wittig-type as well as palladium(0)-copper(I) coupling reactions to construct the carbon skeleton of the target molecules.