97546-41-3Relevant academic research and scientific papers
Calcium ionophores as cardiac stimulants. I. Diacids derived from dibenzo crown ethers
Ball,Cooper,Main
, p. 137 - 143 (2007/10/02)
A series of calcium chelating agents has been prepared based on carboxylic derivatives of open chain 18-Crown-6 analogues. Most of these are efficient calcium binding agents, many form lipophilic calcium complexes, and some of these are capable of releasing Ca2+ from liposomes by ionophore action. The best of these is 1,2-bis-[2-(1-carboxydecyloxy)phenoxy]ethane. This compound is cardiotonic in vitro but in the dog vasoconstriction it is the predominant biological effect.
