97554-76-2

Upstream product

• 15121-89-8 ethyl 3-benzoyl acrylate 
• 762-04-9 phosphonic acid diethyl ester 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 532-27-4 1-chloroacetophenone 
• 70-11-1 α-bromoacetophenone 
• 1008788-80-4 2-(diethoxyphosphoryl)-3-(2-phenyl-[1,3]dioxolan-2-yl)-propionic acid ethyl ester 

Downstream Products

• 1008788-92-8 (2-oxo-5-phenyltetrahydrofuran-3-yl)-phosphonic acid diethyl ester 
• 1027102-74-4 4-iethoxyphosphoryl-2,6-diphenylpyridazin-3(2H)-one 
• 1037575-77-1 3-diethoxyphosphoryl-1-methyl-5-phenylpyrrolidin-2-one 
• 266001-35-8 4-diethoxyphosphoryl-6-phenylpyridazin-3(2H)-one 

Relevant academic research and scientific papers

A general stereoselective method for the synthesis of cyclopropanecarboxylates. A new version of the homologous Horner-Wadsworth- Emmons reaction

The synthesis of α-, β- and γ-substituted α-phosphono-γ-lactones was accomplished using different ring closure and ring homologation strategies. It was found that the lactones could be selectively transformed into the corresponding ethyl cyclopropanecarboxylates by treatment with sodium ethoxide in boiling THF. The reported reaction provides an attractive alternative to the classical homologous Horner-Wadsworth-Emmons approach to the construction of cyclopropanes with electron-withdrawing functionalities. This journal is The Royal Society of Chemistry.

Regioselectivity in the reaction of ethyl diethoxyphosphorylacetate with 1-aryl-2-haloalkan-1-ones: Effective synthesis of 4-aryl-2-diethoxyphosphoryl-4- oxobutanoates

The regioselectivity of the reaction of ethyl diethoxyphosphorylacetate with 1-aryl-2-haloalkan-1-ones has been investigated. It has been found that, depending on the nature of the halogen atom in 1-aryl-2-haloalkan-1-ones and the reaction conditions, alk