97562-27-1

Upstream product

• 108-24-7 acetic anhydride 
• 145593-20-0 (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3S,4R,5R)-3-(diphenoxy-phosphoryloxy)-6-hydroxy-5-(2,2,2-trichloro-ethoxycarbonylamino)-2-(2,2,2-trichloro-ethoxycarbonyloxymethyl)-tetrahydro-pyran-4-yl ester 
• 1078691-95-8 (+)-D-glucosamine hydrochloride 
• 172490-46-9 2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranose 
• 97562-24-8 allyl 2-deoxy-4,6-O-isopropylidene-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 188583-14-4 allyl-2-N-Troc-2-deoxy-α-D-glucopyranoside 
• 97562-25-9 allyl 2-deoxy-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 214050-99-4 (R)-3-Tetradecanoyloxy-tetradecanoic acid (4aR,6S,7R,8R,8aS)-6-allyloxy-2,2-dimethyl-7-(2,2,2-trichloro-ethoxycarbonylamino)-hexahydro-pyrano[3,2-d][1,3]dioxin-8-yl ester 
• 103360-14-1 allyl 2-deoxy-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-6-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 
• 97562-26-0 allyl 2-deoxy-3-O-<(R)-3-tetradecanoyloxytetradecanoyl>-6-O-(2,2,2-trichloroethoxycarbonyl)-2-(2,2,2-trichloroethoxycarbonylamino)-α-D-glucopyranoside 4-(diphenyl phosphate) 
• 105878-46-4 (R)-3-Tetradecanoyltetradecanoic acid 
• 87357-76-4 (R)-3-(dodecanoyloxy)tetradecanoic acid 
• 87357-65-1 (3R)-3-hydroxytetradecanoic acid phenacyl ester 
• 112-64-1 tetradecanoyl chloride 

Downstream Products

• 97562-29-3 (R)-3-Tetradecanoyloxy-tetradecanoic acid (2R,3R,4R,5S,6R)-2-bromo-5-(diphenoxy-phosphoryloxy)-3-(2,2,2-trichloro-ethoxycarbonylamino)-6-(2,2,2-trichloro-ethoxycarbonyloxymethyl)-tetrahydro-pyran-4-yl ester 

Relevant academic research and scientific papers

Total Synthesis of Escherichia coli Lipid A, the Endotoxically Active Principle of Cell-Surface Lipopolysaccharide

Chemical synthesis are described of polyacylated β(1->6) glucosamine disaccharide 1,4'-bis(phosphate), which corresponds to the proposed structure of E. coli lipid A, and of its dephospho derivatives.The synthetic bisphosphate proved to be identical with

Chemical synthesis of 1-dephospho derivative of escherichia coli lipid A

1-Dephospho E. coli lipid A (3) was synthesized and shown to be identical with the corresponding derivative isolated from bacterial cells. This provides the unequivocal evidence supporting the structure of E. coli lipid A (2) recently proposed by us.