97606-30-9

Usage

Organic compound

It is a compound that contains carbon atoms, typically with hydrogen, and may also contain other elements such as oxygen and nitrogen.

Ketones

It belongs to the class of ketones, which are organic compounds characterized by the presence of a carbonyl group (C=O) bonded to two carbon atoms.

Yellow to brown crystalline solid

The physical appearance of the compound, indicating its color and crystal structure.

Molecular weight

265.34 g/mol The mass of one mole of the compound, measured in grams per mole (g/mol).

Potential biological activities

The possibility that the compound may have pharmacological effects or interact with biological systems.

Synthetic intermediate

The compound may be used as a building block or precursor in the synthesis of other, more complex molecules.

Methoxy and dimethylamino groups

The presence of these functional groups in the structure of the compound, which may contribute to its pharmacological properties and potential uses in drug development.

Upstream product

• 55504-32-0 2-(4-(dimethylamino)phenyl)-2-((trimethylsilyl)oxy)acetonitrile 
• 100-10-7 4-dimethylamino-benzaldehyde 

Downstream Products

• 124066-02-0 6-(4-dimethylamino-phenyl)-5-(4-methoxy-phenyl)-2-oxo-1,2-dihydro-pyridine-3-carbonitrile 
• 124065-78-7 6-[4-(dimethylamino)phenyl]-1,2-dihydro-5-(4-methoxyphenyl)-2-oxo-3-pyridinecarboxylic acid 

Relevant academic research and scientific papers

3-Heteroaryl-2-pyridones: Benzodiazepine site ligands with functional selectivity for α2/α3-subtypes of human GABAa receptor-ion channels

A novel series of 3-heteroaryl-5,6-bis(aryl)-1-methyl-2-pyridones were developed with high affinity for the benzodiazepine (BZ) binding site of human γ-aminobutyric acid (GABAA) receptor ion channels, low binding selectivity for α2- and/or α3- over α1-containing GABAA receptor subtypes and high binding selectivity over α5 subtypes. High affinity appeared to be associated with a coplanar conformation of the pyridone and sulfur-containing 3-heteroaryl rings resulting from an attractive S...O intramolecular interaction. Functional selectivity (i.e., selective efficacy) for α2 and/or α3 GABAA receptor subtypes over α1 was observed in several of these compounds in electrophysiological assays. Furthermore, an α3 subtype selective inverse agonist was proconvulsant and anxiogenic in rodents while an α2/α3 subtype selective partial agonist was anticonvulsant and anxiolytic, supporting the hypothesis that subtype selective BZ site agonists may provide new anxiolytic therapies.