97614-45-4

Basic information

• Product Name: 3',5'-Di-O-benzoyl Fialuridine
• Synonyms: 3',5'-Di-O-benzoyl Fialuridine;5-Iodo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine;1-(3,5-Di-O-benzoyl-2-deoxy-2-fluoro-beta-D-arabinofuranosyl)-5-iodo-2,4(1H,3H)-pyrimidinedione
• CAS NO: 97614-45-4
• Molecular Formula: C₂₃H₁₈FIN₂O₇
• Molecular Weight: 564
• Product Categories: Anti-virals;Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals
• Mol File: 97614-45-4.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• Solubility: DMSO, Methanol
• CAS DataBase Reference: 3',5'-Di-O-benzoyl Fialuridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3',5'-Di-O-benzoyl Fialuridine(97614-45-4)
• EPA Substance Registry System: 3',5'-Di-O-benzoyl Fialuridine(97614-45-4)

Safety Data

• Hazardous Substances Data: 97614-45-4(Hazardous Substances Data)

Usage

Chemical Properties

White Solid

Uses

Fialuridine intermediate.

Upstream product

• 97614-44-3 2-deoxy-2-fluoro-3,5-di-O-benzoyl-α-D-arabinofuranosyl bromide 
• 696-07-1 5-iodouracil 
• 97614-42-1 2-O-(imidazolylsulfonyl)-1,3,5-tri-O-benzoyl-α-D-ribofuranose 
• 38953-72-9 5-iodo-2,4-bis-O-trimethylsilyluracil 
• 98855-71-1 ((2R,3R,4S)-3-(benzoyloxy)-5-bromo-4-fluorotetrahydrofuran-2-yl)methyl benzoate 
• 97614-43-2 1,3,5-tri-O-benzoyl-2-deoxy-2-fluoro-α-D-arabinofuranose 

Downstream Products

• 69123-98-4 fialuridine 

Relevant articles and documents

NUCLEOSIDES FOR SUPPRESSING OR REDUCING THE DEVELOPMENT OF RESISTANCE IN CYTOSTATIC THERAPY

The invention relates to special nucleosides, for example, a nucleoside of the formula I, wherein R1-R5 are as described herein, and also to drugs which contain these nucleosides. Furthermore, the invention relates to the use of such nucleosides in a method for suppressing or reducing the formation of resistance in the case of cytostatic treatment of a cancer patient.

Preparation of 5-Iodo- (FIAU) and 5-Astato-1-(2-deoxy-2-fluoro-&β-D-arabinofuranosyl)uracil (FAAU) by a Halodestannylation Reaction

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Fluorocarbohydrates in Synthesis. An Efficient Synthesis of 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)-5-iodouracil (β-FIAU) and 1-(2-Deoxy-2-fluoro-β-D-arabinofuranosyl)thymine (β-FMAU)

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