97618-68-3

Upstream product

• 104-94-9 4-methoxy-aniline 
• 21615-34-9 2-Methoxybenzoyl chloride 
• 6833-21-2 2-methoxy-N-phenylbenzamide 
• 696-62-8 para-iodoanisole 
• 2439-77-2 2-methoxybenzamide 

Downstream Products

• 294629-35-9 3-hydroxy-7-methoxy-3-(4-methoxyphenyl)-2-phenyl-2,3-dihydro-1H-isoindol-1-one 
• 294629-64-4 methyl 7-methoxy-2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-on-3-acetate 
• 294629-56-4 7-methoxy-2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-on-3-acetic acid 
• 294629-40-6 diethyl 7-methoxy-2-(4-methoxyphenyl)-3-phenyl-2,3-dihydro-1H-isoindol-1-on-3-malonate 

Relevant academic research and scientific papers

Activated charcoal supported copper nanoparticles: A readily available and inexpensive heterogeneous catalyst for the N-arylation of primary amides and lactams with aryl iodides

A novel heterogeneous copper catalyst has been developed by supporting copper nanoparticles on activated charcoal via in situ reducing copper(II) with aqueous hydrazine as reductant. The characterization of Cu/C catalyst showed that the Cu0 nano-particles were formed on the surface of charcoal. This catalyst displayed good catalytic activities toward the N-arylation of primary amides and lactams with aryl iodides.

Nickel/Briphos-Catalyzed Direct Transamidation of Unactivated Secondary Amides Using Trimethylsilyl Chloride

Direct transamidation of secondary amides was developed via nickel catalysis. In the presence of trimethylsilyl chloride and manganese, Ni(diglyme)Cl2 with a Briphos ligand efficiently promoted the transamidation of N-aryl benzamide derivatives with primary amines to afford the corresponding secondary amides in moderate to good yields. Primary amines bearing electron-donating groups gave higher yields of the transamidation products.

Optimization and antifungal activity of amide analogues

Using salicylic acid as a lead compound, a series of its analogues (compounds 1-16) were designed and synthesized. Their activity of antipathogenic fungi of plants has been evaluated in the laboratory. The results showed that these compounds had certain antifungal activity against Sclerotinia sclerotiorum and Bipolaris maydis (Nisikado et Miyake) Shoem. Among them, the inhibition of growth for 2-(3- fluorophenylcarbamoyl)phenyl acetate (1) and 2-(3-chlorophenylcarbamoyl)phenyl acetate (2) reached 91.1 %, 92.8 % and 90.1 %, 90.1 % at a concentration of 100 mg L-1, respectively.

Benzoisothiazolone compositions

A composition, suitable for topical application to the skin, containing at least one benzoisothiazolone of formula (I): Novel benzoisothiazolones of formula (I) and a method of caring for dry and/or mature skin.

Substituted 2-phenyl-4-quinolone-3-carboxylic acid compounds and their use as antitumor agents

Substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives and their salts were synthesized. The results of preliminary screening revealed that these compounds are potent in killing solid tumor cancers.