Welcome to LookChem.com Sign In|Join Free

CAS

  • or

97643-35-1

Post Buying Request

97643-35-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

97643-35-1 Usage

Description

5(S),6(R),15(S)-TRIHETE METHYL ESTER, also known as Lipoxin A4 methyl ester (LXA4 methyl ester), is a lipid-soluble prodrug formulation of the transcellular metabolite LXA4. LXA4 is a trihydroxy fatty acid containing a conjugated tetraene, produced by the metabolism of 15-HETE or 15-HpETE with human leukocytes. It is equipotent to leukotriene B4 (LTB4) in inducing superoxide generation in human neutrophils at 0.1 μM and is associated with several biological functions, including leukocyte activation, chemotaxis effects, natural killer cell inhibition, and monocyte migration and adhesion.

Uses

Used in Pharmaceutical Industry:
5(S),6(R),15(S)-TRIHETE METHYL ESTER is used as a prodrug formulation for enhancing the lipid solubility and bioavailability of LXA4, allowing for better absorption and distribution in the body. This leads to improved therapeutic outcomes in various inflammatory and immune-related conditions.
Used in Inflammatory Disease Treatment:
5(S),6(R),15(S)-TRIHETE METHYL ESTER is used as an anti-inflammatory agent for the treatment of various inflammatory diseases. Its ability to modulate leukocyte activation, chemotaxis, and other immune functions helps in reducing inflammation and promoting tissue repair.
Used in Immune Regulation:
5(S),6(R),15(S)-TRIHETE METHYL ESTER is used as an immune modulator to regulate the immune response in various conditions. Its effects on natural killer cell inhibition and monocyte migration and adhesion contribute to the fine-tuning of the immune system and prevention of excessive immune reactions.
Used in Drug Delivery Systems:
5(S),6(R),15(S)-TRIHETE METHYL ESTER can be incorporated into drug delivery systems to improve the targeting and efficacy of LXA4 in specific tissues and cells. This can lead to better treatment outcomes and reduced side effects in various therapeutic applications.

Check Digit Verification of cas no

The CAS Registry Mumber 97643-35-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,6,4 and 3 respectively; the second part has 2 digits, 3 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 97643-35:
(7*9)+(6*7)+(5*6)+(4*4)+(3*3)+(2*3)+(1*5)=171
171 % 10 = 1
So 97643-35-1 is a valid CAS Registry Number.

97643-35-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5(S),6(R),15(S)-TRIHETE METHYL ESTER

1.2 Other means of identification

Product number -
Other names 5S,6R,15S-TRIHYDROXY-7E,9E,11Z,13E-EICOSATETRAENOIC ACID,METHYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:97643-35-1 SDS

97643-35-1Upstream product

97643-35-1Relevant articles and documents

Stereoselective total synthesis of 5(S), 6(R), 15(S)-trihydroxy-7(E), 9(E), 11(Z), 13(E)-eicosatetraenoic acid (Lipoxin A)

Yadav,Barma,Dutta, Dinah

, p. 143 - 146 (2007/10/03)

A stereoselective synthesis of the title compound from D-xylose using zinc mediated deoxygenation of 4-hydroxy-2-butenoic acid moiety and base induced double elimination of 4,5-epoxy allyl chloride as key steps is described.

SIMPLE SYNTHESIS AND ASSIGNMENT OF STEREOCHEMISTRY OF LIPOXIN A

Corey, E. J.,Su, Wei-gou

, p. 281 - 284 (2007/10/02)

A synthesis of lipoxin A, a recently descovered biologically active eicosanoid, and the assignment of stereoformula 1 is reported herein.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 97643-35-1