97657-92-6 Usage
Uses
Used in Neurodegenerative Applications:
2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride is used as a neuroprotective agent for the treatment of neurodegenerative conditions such as Alzheimer's disease. It has been shown to target the mitochondria and restore mitochondrial function, leading to improved neuronal survival and reduced oxidative stress. Additionally, it has demonstrated anti-amnesic properties, potentially improving memory and cognitive function in patients with neurodegenerative disorders.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2,3,4,5-Tetrahydro-2,8-dimethyl-5-[2-(6-methyl-3-pyridyl)ethyl]-1H-pyrido[4,3-b]indole dihydrochloride is used as a drug candidate for the development of novel therapeutic agents targeting neurodegenerative conditions. Its unique properties and potential to modulate mitochondrial function make it a valuable compound for further research and development in the field of neurodegenerative disease treatment.
Biological Activity
Non-selective antihistamine that displays cognitive enhancing abilities. Also displays high affinity for 5-HT (particularly 5-HT 6 and 5-HT 7 ), α -adrenergic, dopaminergic, AMPA and NMDA receptors, and L-type calcium channels. Exhibits neuroprotective activity in cellular models of Alzheimer's and Huntington's disease and preserves cognitive function following administration to AF64A lesioned rats. Protects neurons against the neurotoxic action of β -amyloid fragment.
Check Digit Verification of cas no
The CAS Registry Mumber 97657-92-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,6,5 and 7 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 97657-92:
(7*9)+(6*7)+(5*6)+(4*5)+(3*7)+(2*9)+(1*2)=196
196 % 10 = 6
So 97657-92-6 is a valid CAS Registry Number.
InChI:InChI=1/C21H25N3.ClH/c1-15-4-7-20-18(12-15)19-14-23(3)10-9-21(19)24(20)11-8-17-6-5-16(2)22-13-17;/h4-7,12-13H,8-11,14H2,1-3H3;1H