97672-26-9Relevant articles and documents
Semisynthesis of ingenol 3-angelate (PEP005): Efficient stereoconservative angeloylation of alcohols
Liang, Xifu,Grue-Sorensen, Gunnar,Petersen, Anders Klarskov,H?gberg, Thomas
, p. 2647 - 2652 (2013/01/15)
A high-yielding method was developed for the preparation of ingenol 3-angelate (PEP005, ingenol mebutate) via the corresponding 5,20-acetonide without concomitant isomerization of the angelate (Z-form) to the corresponding tiglate (E-form). The general sc
Synthetic studies on thiostrepton: Construction of thiostrepton analogues with the thiazoline-containing macrocycle
Nicolaou,Nevalainen, Marta,Zak, Mark,Bulat, Stephan,Bella, Marco,Safina, Brian S.
, p. 3418 - 3424 (2007/10/03)
Leading the way: The novel thiostrepton analogue 1 and its 5S, 6S diastereomer were synthesized through macrolactamization reactions. Forays towards the total synthesis of the natural product itself should follow a similar strategy.
A New and Efficient Esterification Reaction via Mixed Anhydrides by the Promotion of a Catalytic Amount of Lewis Acid
Miyashita, Mitsutomo,Shiina, Isamu,Miyoshi, So,Mukaiyama, Teruaki
, p. 1516 - 1527 (2007/10/02)
In the presence of a catalytic amount of Lewis acid, various carboxylic esters or S-phenyl carbothioates are prepared in excellent yields by the respective reactions of equimolar amounts of silyl carboxylates and alkyl silyl ethers or phenyl silyl sulfides with 4-trifluoromethylbenzoic anhydride.
