97677-86-6

Upstream product

• 97677-84-4 α-Benzyl-γ-hydroxy-valerol 
• 164168-29-0 4-Benzyl-2-methoxy-2-methyl-tetrahydro-furan 
• 194493-32-8 [(E)-3-(2-Bromo-1-methoxy-1-methyl-ethoxy)-propenyl]-benzene 
• 6049-46-3 2-Benzyl-4-oxopentanoic acid 
• 97677-88-8 2-Benzyl-2-(2-oxo-propyl)-malonic acid diethyl ester 
• 14557-92-7 2-(2-phenylmethyl)-4-methyl-4-butanolide 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 

Relevant academic research and scientific papers

Tributyltin chloride-sodium cyanoborohydride mediated tandem radical cyclisation-reductive demethoxylation sequence

Reaction of the bromoketals 3, 7a-g and 11 with tri-n-butyltin chloride and sodium cyanoborohydride in the presence of a catalytic amount of AIBN furnished the ethers 5, 8a-g and 13 via a tandem sequence comprising of a radical cyclisation reaction and tri-n-butylhalostannane and sodium cyanoborohydride mediated reductive demethoxylation of the resulting cyclic ketals.

CYCLODESHYDRATION DE DIOLS EN PRESENCE D'HMPT1

1,4 and 1,5-diols heated with 0.3 equivalent of HMPA undergo cyclodehydration leading to tetrahydrofurans and tetrahydropyrans.