97717-40-3

Upstream product

• 555-16-8 4-nitrobenzaldehdye 
• 1226-42-2 1,2-bis(4-methoxyphenyl)-1,2-ethanedione 
• 1448032-45-8 4,5-dibromo-1-{[2-(trimethylsilyl)ethoxy]methyl}-2-(4-nitrophenyl)-1H-imidazole 
• 1448032-65-2 4,5-di(4-methoxyphenyl)-1-{[2-(trimethylsilyl)ethoxy]methyl}-2-(4-nitrophenyl)-1H-imidazole 

Downstream Products

• 107701-39-3 4,5-bis(4-methoxyphenyl)-1-methyl-2-(4-nitrophenyl)-1H-imidazole 
• 97717-41-4 4,5-bis(4-methoxyphenyl)-2-(4-nitrophenyl)imidazolium acetate dihydrate 
• 132287-33-3 4,5-Bis-(4-methoxy-phenyl)-2-(4-nitro-phenyl)-1H-imidazole; compound with [1,4]dioxane 

Relevant academic research and scientific papers

Facile fabrication of porous magnetic covalent organic frameworks as robust platform for multicomponent reaction

The design of cheap yet efficient nanoporous magnetic catalysts for the environmentally benign process's widespread application is an extremely attractive, challenging chemical research field. A novel porous magnetic covalent organic framework was prepared by the condensation reaction of melamine and terephthaladehyde on the surface of 3,4-dihydroxybenzaldehyde coated magnetic Fe3O4 nanoparticles COF@Fe3O4 under hydrothermal conditions for the first time. The high surface area magnetic COF could exhibit superior catalytic activity for sustainable synthesis of trisubstituted and tetrasubstituted imidazoles and pyrroles in good to excellent yields in PEG as solvent under environmentally friendly, ambient conditions and making the overall process economical, efficient, and green. The retrievable catalyst in PEG is general and applicable to a broad substrate scope and functional group compatibility. The structure and morphology of the COF@Fe3O4 were characterized by FTIR, XRD, EDX, and SEM spectroscopy. The COF@Fe3O4 magnetic catalyst was recovered by an external magnet and used for several cycles without significant catalytic activity loss.

Selective sequential cross-coupling reactions on imidazole towards neurodazine and analogues

Polysubstituted imidazoles represent a common structural motif in bioactive molecules. A modular and flexible strategy towards 2,4,5-triarylated imidazoles is reported applying a Suzuki-Miyaura cross-coupling protocol. Employing 1-protected 2,4,5-tribromoimidazole as starting material, both stepwise and one-pot protocols towards the title compounds are disclosed. The utility of the approach was demonstrated by synthesizing neurodazine, a biologically active molecule affecting neuronal cell differentiation.

Novel charge-transfer chromophores featuring imidazole as Π-linkage

Overall 21 imidazole-based chromophores have been synthesized and fully characterized. The imidazole core was systematically substituted with donors (NMe2 and OMe) and acceptors (NO2 and CN groups) additionally separated from the imi

New class of imidazoles incorporated with thiophenevinyl conjugation pathway for robust nonlinear optical chromophores

A new series of thermally stable heterocyclic imidazole-based nonlinear optical chromophores has been developed. These chromophores possess a thiophene based stilbene conjugation pathway with a nitro acceptor group attached to the phenyl end. This feature leads to robust chromopores with high thermal stability and enhanced molecular nonlinearity.

Chromotropism of Imidazole Derivatives. Part 1. 4,5-Bis-(4-methoxyphenyl)-2-(4-nitrophenyl)imidazolium Acetate Dihydrate

4,5-Bis(4-methoxyphenyl)-2-(4-nitrophenyl)imidazolium acetate dihydrate (1) in the crystalline state exhibits a sensitive colour change from orange-yellow to red on treatment by various methods (drying, trituration, or heating).The colour change was reversible below 70 deg C but above 70 deg C the change was irreversible and the colour deepended.Compound (1) was deprotonated with the loss of one mole of water of crystallization under treatment and can revert to the original by absorption of one mole of water.On heating to 100 deg C, (1) lost all solvent of crystallization to give a deep red material (2). (2) Was considered to be 4,5-bis-(4-methoxyphenyl)-2-(4-nitrophenyl)imidazole which was linked by hydrogen bond from the imino group in one molecule to the nitro oxygen in another.Compound (2) reverted to (1) in saturated AcOH-H2O vapour.