97724-22-6Relevant academic research and scientific papers
Synthetic thiosemicarbazones as a new class of Mycobacterium tuberculosis protein tyrosine phosphatase A inhibitors
Sens, Larissa,de Souza, Ana Caroline Arruda,Pacheco, Lucas Antonio,Menegatti, Angela Camila Orbem,Mori, Mattia,Mascarello, Alessandra,Nunes, Ricardo José,Terenzi, Hernán
, p. 5742 - 5750 (2018/11/03)
Mycobacterium tuberculosis secretes two protein tyrosine phosphatases as virulence factors, PtpA and PtpB. Inhibition studies of these enzymes have shown significant attenuation of the M. tuberculosis growth in vivo. As PtpA mediates many effects on the r
