97729-66-3

Usage

InChI:InChI=1/C8H10ClNO4S/c1-8(2)4(7(12)13)10-5(11)3(9)6(10)15(8)14/h3-4,6H,1-2H3,(H,12,13)/t3-,4-,6+,15?/m0/s1

Upstream product

• 20097-86-3 6-chloropenicillanic acid 
• 551-16-6 6-Aminopenicillanic Acid 
• 228850-81-5 6α-chloropenicillanic acid tert-butyl ester (S)-sulfoxide 

Relevant academic research and scientific papers

Preparation of tert-butyl 6-aminopenicillanate and its 6-oxo and 6- diazo derivatives

A 1:1 1,4-dioxane-tert-butyl acetate mixture and BF3 etherate were used for an effective 6-aminopenicillanic acid conversion into the tert-butyl ester (64 ± 3% yield) which could be easily transformed into tert-butyl 6- oxo-and 6-diazo-penicillanates.

Preparation method of 6-chloropenicillin sulfoxide diphenylmethyl ester and application thereof

The invention provides a preparation method of 6-chloropenicillin sulfoxide diphenylmethyl ester and application thereof. The preparation method comprises the following steps that in mixed liquid of hydrochloric acid and alcohol, 6-APA and sodium nitrite

β-Lactams on solid support: Mild and efficient removal of penicillin derivatives from Merrifield resin using aluminum chloride

Penicillin derivatives linked to Merrifield resin are efficiently released from this support under mild conditions using aluminum chloride in dichloromethane/nitromethane. Extension to Wang resin-linked analogues and studies on the solid-phase oxidation of penicillin is also reported.