97732-34-8Relevant academic research and scientific papers
URACIL NUCLEOTIDE ANALOGUES, THEIR PREPARATION METHOD AND USE THEREOF
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Page/Page column 51, (2016/10/08)
The invention relates to uracil nucleotide analogues, their preparation method and use thereof. Specifically, the invention provides the uracil nucleotide analogues with the formula (I), their stereoisomers and pharmaceutical acceptable salts, the preparation method and use. These compounds are RNA-dependent RNA viral replication inhibitors, and can be used as HCV NS5B polymerase inhibitors, HCV replication inhibitors as well as for the treatment of hepatitis C infection in mammals. They have broad application prospects and are expected to develop a new generation of antiviral drugs.
