97755-45-8Relevant academic research and scientific papers
Chiral N-heterocyclic carbene/pyridine ligands for the iridium-catalyzed asymmetric hydrogenation of olefins
Schumacher, Andreas,Bernasconi, Maurizio,Pfaltz, Andreas
supporting information, p. 7422 - 7425 (2013/07/26)
Swapping N,P for C,N: Iridium complexes of bidentate pyridine-based C,N ligands with an N-heterocylic carbene (NHC) unit proved to be efficient and highly enantioselective hydrogenation catalysts. As a result of the lower acidity of iridium hydride intermediates produced from NHC-based complexes, these catalysts are much better suited than analogous N,P-ligand complexes for the hydrogenation of acid-sensitive substrates. Copyright
Chichibabin-type direct alkylation of pyridyl alcohols with alkyl lithium reagents
Jeffrey, Jenna L.,Sarpong, Richmond
supporting information, p. 5400 - 5403,4 (2012/12/12)
Direct C(6) alkylation of pyridyl alcohols can be achieved following an initial deprotonation of the hydroxy group. This transformation, which is believed to occur by a Chichibabin-type alkylation, avoids lateral deprotonation prior to pyridine ring alkylation and gives increased regioselectivity for C(6) over C(4) alkylation.
Chichibabin-type direct alkylation of pyridyl alcohols with alkyl lithium reagents
Jeffrey, Jenna L.,Sarpong, Richmond
supporting information, p. 5400 - 5403 (2013/01/15)
Direct C(6) alkylation of pyridyl alcohols can be achieved following an initial deprotonation of the hydroxy group. This transformation, which is believed to occur by a Chichibabin-type alkylation, avoids lateral deprotonation prior to pyridine ring alkylation and gives increased regioselectivity for C(6) over C(4) alkylation.
