97760-77-5 Usage
Uses
Used in Pharmaceutical Industry:
Ethanone, 1-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]is used as a key intermediate in the synthesis of pharmaceuticals for its potential to contribute to the development of novel therapeutic agents. Its unique structural features allow for the creation of molecules with diverse pharmacological profiles, making it a valuable asset in medicinal chemistry.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, Ethanone, 1-[4-amino-3-bromo-5-(trifluoromethyl)phenyl]- serves as a structural precursor for the design and synthesis of new molecules with potential therapeutic applications. Its reactivity and the presence of functional groups make it suitable for further chemical modifications, leading to the discovery of innovative drugs.
Check Digit Verification of cas no
The CAS Registry Mumber 97760-77-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,7,6 and 0 respectively; the second part has 2 digits, 7 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 97760-77:
(7*9)+(6*7)+(5*7)+(4*6)+(3*0)+(2*7)+(1*7)=185
185 % 10 = 5
So 97760-77-5 is a valid CAS Registry Number.
97760-77-5Relevant academic research and scientific papers
Synthesis of further amino-halogen-substituted phenyl-aminoethanols
Kruger,Keck,Noll,Pieper
, p. 1612 - 1624 (2007/10/02)
Starting from clenbuterol as a lead structure, new 4-amino-phenyl-aminoethanol analogues have been synthesized by different approaches. In these compounds one or both of the chlorine atoms of clenbuterol are replaced by other residues. This has led to compounds with high intrinsic β2-mimetic and/or β1-blocking activities. 1-(4-Amino-3-chloro-5-trifluoromethyl-phenyl)-2-tert.-butylamino-ethanol hydrochloride (mabuterol) has been selected for clinical development. A detailed description is also given of the syntheses of new intermediate acetophenone derivatives as well as of the resolution of mabuterol into its enantiomers.
