97782-03-1 Usage
General Description
2-Aminoformycin is a chemical compound that belongs to the class of nucleosides, which are the building blocks of nucleic acids like DNA and RNA. It is a metabolite derived from Streptomyces griseus and exhibits antitumor activity by inhibiting the synthesis of nucleotides, the building blocks of DNA and RNA. 2-aminoformycin has been of interest in cancer research due to its potential as a chemotherapeutic agent. It works by interfering with the replication and transcription of DNA, preventing cancer cells from multiplying and spreading. 2-Aminoformycin has shown promise in preclinical studies as a potential treatment for various types of cancer, making it a focus of ongoing research in the field of oncology.
Check Digit Verification of cas no
The CAS Registry Mumber 97782-03-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,7,8 and 2 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 97782-03:
(7*9)+(6*7)+(5*7)+(4*8)+(3*2)+(2*0)+(1*3)=181
181 % 10 = 1
So 97782-03-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H14N6O4/c11-9-5-3(13-10(12)14-9)4(15-16-5)8-7(19)6(18)2(1-17)20-8/h2,6-8,17-19H,1H2,(H,15,16)(H4,11,12,13,14)/t2-,6-,7-,8+/m1/s1
97782-03-1Relevant articles and documents
2-Fluoroformycin and 2-Aminoformycin. Synthesis and Biological Activity
Secrist, John A.,Shortnacy, Anita T.,Montgomery, John A.
, p. 1740 - 1742 (2007/10/02)
Syntheses of 2-fluoroformacin pyrimidine> (2b) and 2-aminoformacin pyrimidine> (2c) are described.Cytotoxicity data are given for 2b and 2c alone as well as with added pentostatin.Kinetic parameters for adenosine deaminase are also provided. 2-Fluoroformycin, although a much poorer substrate for adenosine deaminase than formycin A, is not nearly as cytotoxic to cells in culture.
