97806-72-9

Upstream product

• 122689-39-8 Methyl (5R*,6R*,7R*)-5,6-Dimethylbicyclo<4.3.0>non-1-ene-7-carboxylate 
• 122689-38-7 (1S,7S,7aR)-4-Hydroxy-7,7a-dimethyl-octahydro-indene-1-carboxylic acid methyl ester 
• 97763-46-7 (1S,3aR,7R,7aR)-1-Isopropenyl-7,7a-dimethyl-octahydro-inden-4-one 
• 97763-46-7 (1S,3aS,7R,7aR)-1-Isopropenyl-7,7a-dimethyl-octahydro-inden-4-one 
• 97763-51-4 1-((1R,3aR,4S,7R,7aS)-4-Hydroxy-7,7a-dimethyl-octahydro-inden-1-yl)-ethanone 
• 97763-51-4 1-((1R,3aS,4R,7R,7aS)-4-Hydroxy-7,7a-dimethyl-octahydro-inden-1-yl)-ethanone 
• 97763-48-9 (1S,3aR,4S,7R,7aR)-1-Isopropenyl-7,7a-dimethyl-octahydro-inden-4-ol 
• 97763-48-9 (1S,3aS,4R,7R,7aR)-1-Isopropenyl-7,7a-dimethyl-octahydro-inden-4-ol 
• 97763-45-6 Acetic acid (1S,7R,7aR)-1-isopropenyl-7,7a-dimethyl-2,3,5,6,7,7a-hexahydro-1H-inden-4-yl ester 
• 97763-54-7 1-((1S,7S,7aS)-7,7a-Dimethyl-2,3,5,6,7,7a-hexahydro-1H-inden-1-yl)-ethanone 
• 97777-79-2 3,4-Dimethyl-2-(4-methyl-pent-3-enyl)-cyclohex-2-enone 
• 122689-37-6 (1R,3aR,7R,7aS)-3-Hydroxy-7,7a-dimethyl-4-oxo-octahydro-indene-1-carboxylic acid methyl ester 
• 122689-38-7 (1S,3aR,7S,7aR)-4-Hydroxy-7,7a-dimethyl-octahydro-indene-1-carboxylic acid methyl ester 
• 122689-35-4 methyl (1R*,2R*,9R*)-1,2-dimethyl-5-oxobicyclo<4.3.0>non-6-ene-9-carboxylate 

Relevant academic research and scientific papers

Synthesis of chiloscyphones and the biological activities of their synthetic intermediates against methicillin-resistant Staphylococcus aureus (MRSA)

The total syntheses of chiloscyphone (1) and isochiloscyphone (2) have been achieved. Furthermore, the synthetic intermediate 5 shows biological activity against methicillin-resistant Staphyrococcus aureus, and compounds 5, 17, and 18, display imipenem-ty

A new approach to the bicyclo[4.3.0] ring system of natural products from the liverwort: Total synthesis of (±)-chiloscyphone and (±)-isochiloscyphone

Tricyclic intermediate 5 was synthesized by using the intramolecular Diels-Alder reaction as the key step. Total synthesis of (±)- chiloscyphone and (±)-isochiloscyphone was accomplished. Construction of the tricyclic derivative 5, a common intermediate f

A new annulation method. Total syntheses of the sesquiterpenoids (+/-)-chiloscyphone and (+/-)-6-epi-chiloscyphone

The efficacy of a new annulation method, developed for the construction of functionalized bicyclic compounds, is illustrated by conversion of the β-keto esters 18 and 19 into the bicyclonon-1-enes 33 and 34, respectively, and by transformation of 2-methoxycarbonylcyclopentanone (20) into the bicyclonon-6-ene 38 and the bicyclodec-7-enes 48 and 51.Application of the method to total syntheses of the structurally unusual sesquiterpenoids (+/-)-chiloscyphone (16) and (+/-)-6-epi-chiloscyphone (17) is described.

Total Synthesis of (-)-Chiloscyphone, Sesquiterpenoid Isolated from the Liverwort. Absolute Configuration of (-)-Chiloscyphone and (+)-Chiloscypholone

The absolute configurations of (-)-chiloscyphone and (+)-chiloscypholone isolated from the liverwort Chiloscyphus polyanthos and C. pallescens respectively, have been determined by the total synthesis of the optically active compound.The 1,4-addition of v

Total Sythesis of Liverwort Sesquiterpene Ketone (+/-)-Chiloscyphone via Intramolecular Aldol Condensation

(+/-)-Chiloscyphone, a sesquiterpene ketone isolated from the liverwort, has been synthesized starting from 3,4-dimethyl-2-cyclohexen-1-one via intramolecular aldol condensation.

SYNTHESE DES SESQUITERPENS (+/-)-CHILOSCYPHON

The revised structure of chiloscyphone (1) is confirmed by total synthesis: 4a,b, obtained by stereoselective cyclization of 2, were transformed to 8.Ketone 8 was converted to (+/-)-1 by direct α-methylenation.