97825-24-6

Basic information

• Product Name: fosinopril
• CAS NO: 97825-24-6
• Molecular Formula: C30H46NO7P
• Molecular Weight: 563.66
• Product Categories: Fosinopril
• Mol File: 97825-24-6.mol
• Article Data: 5

Chemical Properties

• Appearance: /
• CAS DataBase Reference: fosinopril(CAS DataBase Reference)
• NIST Chemistry Reference: fosinopril(97825-24-6)
• EPA Substance Registry System: fosinopril(97825-24-6)

Safety Data

• Hazardous Substances Data: 97825-24-6(Hazardous Substances Data)

Upstream product

• 31560-20-0 (2S,4R)-1-benzoyl-4-hydroxypyrrolidine-2-carboxylic acid methyl ester 
• 128948-00-5 C₁₉H₂₉O₆P 
• 103201-78-1 (2S,4S)-4-cyclohexylpyrrolidine-2-carboxylic acid 
• 96314-26-0 trans-4-phenyl-L-proline 
• 120851-71-0 (2S,4S)-1-Benzoyl-4-phenyl-pyrrolidine-2-carboxylic acid 
• 90657-55-9 trans-4-cyclohexyl-L-proline hydrochloride 

Relevant articles and documents

Preparation methods of antihypertensive Fosinopril sodium and key intermediate thereof

The invention relates to preparation methods of an antihypertensive Fosinopril sodium and a key intermediate thereof trans-4-phenyl-L-proline suitable for industrial production. Synthesis of the key intermediate trans-4-phenyl-L-proline has high chiral selectivity, and the method is simple and easy to operate.

Process for the preparation of fosinopril and intermediates thereof

The present invention relates to a process for the preparation of intermediates useful in the synthesis of [1[S(R)],2α,4β]-4-cyclohexyl-1-[[[2-methyl-1-oxypropoxy) propoxy](4-phenylbutyl phosphinyl]acetyl]-L-proline, and the synthesis thereof, in particular as sodium salt (fosinopril sodium).

Process for the preparation of fosinopril and intermediates thereof

Process for the preparation of intermediates useful in the synthesis of [1[S(R)],2α,4β]-4-cyclohexyl-1-[[[(2-methyl-1-oxypropoxy) propoxy](4-phenylbutyl) phosphinyl]acetyl]-L-proline, and the synthesis thereof, in particular as sodium salt.