97945-27-2 Usage
General Description
(2-Phenyl-1H-indol-3-yl)-acetaldehyde, also known as indole-3-acetaldehyde, is a chemical compound with a complex structure consisting of a phenyl group, an indole ring, and an acetaldehyde functional group. It is commonly used in organic synthesis and pharmaceutical research as a building block for various chemical reactions. (2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE has been studied for its potential biological activities, including its role as a precursor to the auxin hormone in plants, as well as its potential for anti-inflammatory and anti-cancer properties. Additionally, (2-Phenyl-1H-indol-3-yl)-acetaldehyde has also been investigated for its potential role in the development of new drugs and pharmaceutical compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 97945-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,9,4 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 97945-27:
(7*9)+(6*7)+(5*9)+(4*4)+(3*5)+(2*2)+(1*7)=192
192 % 10 = 2
So 97945-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO/c18-11-10-14-13-8-4-5-9-15(13)17-16(14)12-6-2-1-3-7-12/h1-9,11,17H,10H2
97945-27-2Relevant articles and documents
Relay Catalysis of Bismuth Trichloride and Byproduct Hydrogen Bromide Enables the Synthesis of Carbazole and Benzo[α]carbazoles from Indoles and α-Bromoacetaldehyde Acetals
Wu, Fengtian,Huang, Wenbo,Yiliqi,Yang, Jian,Gu, Yanlong
, p. 3318 - 3330 (2018/08/01)
Benzo[α]carbazoles were synthesized from 2-phenylindoles and α-bromoacetaldehyde using bismuth trichloride as a catalyst. The reaction was triggered by a bismuth trichloride-catalyzed Friedel-Crafts alkylation of these two precursors, which provided a tryptaldehyde intermediate that underwent intramolecular olefination to form the final product. Interestingly, the HBr byproduct generated in the upstream step of the reaction catalyzed the following downstream reaction steps, thus creating a byproduct-participated relay catalytic process. Motivated by this mechanism, we developed a three-component reaction of indole, α-bromoacetaldehyde acetal, and 1,3-dicarbonyl compounds. This study offers a straightforward method for synthesizing substituted carbazoles. (Figure presented.).
