97945-27-2 Usage
Uses
Used in Organic Synthesis:
(2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE is used as a key intermediate in organic synthesis for its ability to participate in numerous chemical reactions, facilitating the creation of a broad range of chemical products.
Used in Pharmaceutical Research:
In Pharmaceutical Research, (2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE is used as a building block for the development of new drugs, leveraging its complex structure to explore novel therapeutic agents.
Used in Plant Biology:
(2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE is used as a precursor to the auxin hormone in plants, playing a crucial role in plant growth and development.
Used in Anti-inflammatory Applications:
(2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE is used as a potential anti-inflammatory agent, given its biological activities that may help in reducing inflammation.
Used in Anti-cancer Applications:
In Anti-cancer Applications, (2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE is used for its potential to contribute to the development of new cancer treatments, based on its biological properties.
Used in Drug Development:
(2-PHENYL-1H-INDOL-3-YL)-ACETALDEHYDE is used in drug development for its potential role in creating new pharmaceutical compounds, indicating its importance in advancing medical treatments.
Check Digit Verification of cas no
The CAS Registry Mumber 97945-27-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,7,9,4 and 5 respectively; the second part has 2 digits, 2 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 97945-27:
(7*9)+(6*7)+(5*9)+(4*4)+(3*5)+(2*2)+(1*7)=192
192 % 10 = 2
So 97945-27-2 is a valid CAS Registry Number.
InChI:InChI=1/C16H13NO/c18-11-10-14-13-8-4-5-9-15(13)17-16(14)12-6-2-1-3-7-12/h1-9,11,17H,10H2
97945-27-2Relevant academic research and scientific papers
Relay Catalysis of Bismuth Trichloride and Byproduct Hydrogen Bromide Enables the Synthesis of Carbazole and Benzo[α]carbazoles from Indoles and α-Bromoacetaldehyde Acetals
Wu, Fengtian,Huang, Wenbo,Yiliqi,Yang, Jian,Gu, Yanlong
, p. 3318 - 3330 (2018/08/01)
Benzo[α]carbazoles were synthesized from 2-phenylindoles and α-bromoacetaldehyde using bismuth trichloride as a catalyst. The reaction was triggered by a bismuth trichloride-catalyzed Friedel-Crafts alkylation of these two precursors, which provided a tryptaldehyde intermediate that underwent intramolecular olefination to form the final product. Interestingly, the HBr byproduct generated in the upstream step of the reaction catalyzed the following downstream reaction steps, thus creating a byproduct-participated relay catalytic process. Motivated by this mechanism, we developed a three-component reaction of indole, α-bromoacetaldehyde acetal, and 1,3-dicarbonyl compounds. This study offers a straightforward method for synthesizing substituted carbazoles. (Figure presented.).
CONVERSION OF INDOLES INTO QUINOLINES THROUGH THE N-1-C-2 FISSION BY SINGLET-OXYGEN AS A MODEL EXPERIMENT OF BIOMIMETIC SYNTHESIS OF QUININE ALKALOIDS
Ihara, Masataka,Noguchi, Kazuharu,Fukumoto, Keiichiro,Kametani, Tetsuji
, p. 2109 - 2114 (2007/10/02)
Photo-oxygenation of indole-3-acetaldehydes (28-30) followed by treatments with dimethyl sulphide and then dilute acetic acid gave 4-acylquinolines (13, 31 and 32), respectively.
