98009-34-8Relevant academic research and scientific papers
Lipoxins A4 and B4. Total Synthesis Including Deprotection Studies
Gravier-Pelletier, Christine,Dumas, Jacques,Merrer, Yves Le,Depezay, Jean-Claude
, p. 2441 - 2452 (2007/10/02)
The total synthesis of lipoxins A4 and B4 (LXA4 and LXB4) as well as of their all-trans isomers is reported.A study concerning the final steps of deprotection of silyl ether, cyclic carbonate and ethyl ester assisted by a high-speed scanning UV spectropho
TOTAL SYNTHESIS OF LIPOXINS A4 AND B4 FROM D-ISOASCORBIC ACID
Gravier-Pelletier, C.,Dumas, J.,Merrer, Y. Le,Depezay, J. C.
, p. 1165 - 1168 (2007/10/02)
A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure α-hydroxy and α,β-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material.Connection by a six carbons unit uses Wittig-type reaction
TOTAL SYNTHESIS OF LIPOXIN B: ASSIGNMENT OF STEREOCHEMISTRY
Leblanc, Yves,Fitzsimmons, Brian,Adams, Julian,Rokach, Joshua
, p. 1399 - 1402 (2007/10/02)
Four isomers of lipoxin B were synthesized using carbohydrate precursors.An authentic sample of lipoxin B (from human leukocytes) was found to be a mixture of all-trans isomers 1a and 1c.
