98049-66-2

Upstream product

• 98009-30-4 (4R,5S)-4-Hydroxymethyl-5-pentyl-[1,3]dioxolan-2-one 
• 133988-95-1 (S)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-pent-2-ynoic acid ethyl ester 
• 79308-43-3 (S)-5-((R)-2,2-Dimethyl-[1,3]dioxolan-4-yl)-5-hydroxy-pentanoic acid ethyl ester 
• 72036-30-7 ethyl 3-lithiopropiolate 
• 93292-41-2 2-deoxy-3-O-(tert-butyldiphenylsilyl)-4,5-O-isopropylidene-D-erythro-pentose diethyl dithioacetal 
• 93292-42-3 2-deoxy-3-O-(tert-butyldiphenylsilyl)-4,5-bis-O-(1-methylethylidene)-D-erythro-pentose 
• 89408-79-7 (2R,3S)-1-(tert-Butyl-diphenyl-silanyloxy)-octane-2,3-diol 
• 98009-32-6 (2E,4E)-5-((4R,5S)-2-Oxo-5-pentyl-[1,3]dioxolan-4-yl)-penta-2,4-dienal 
• 98009-31-5 (4S,5S)-2-Oxo-5-pentyl-[1,3]dioxolane-4-carbaldehyde 
• 98009-29-1 (4R,5S)-4-(tert-Butyl-diphenyl-silanyloxymethyl)-5-pentyl-[1,3]dioxolan-2-one 
• 98009-22-4 Ethyl (5S,6R)-5-tert-Butyldiphenylsilyloxy-6,7-O-isopropylideneheptanoate 
• 98009-23-5 (5S,6R)-5-(tert-Butyl-diphenyl-silanyloxy)-6,7-dihydroxy-heptanoic acid ethyl ester 
• 98009-26-8 (E)-(S)-8-Bromo-5-(tert-butyl-diphenyl-silanyloxy)-oct-6-enoic acid ethyl ester 
• 98009-25-7 ethyl (5S)-(6E)-5-tert-butyldiphenylsilyloxy-8-hydroxy-6-octenoate 

Relevant academic research and scientific papers

Lipoxins A4 and B4. Total Synthesis Including Deprotection Studies

The total synthesis of lipoxins A4 and B4 (LXA4 and LXB4) as well as of their all-trans isomers is reported.A study concerning the final steps of deprotection of silyl ether, cyclic carbonate and ethyl ester assisted by a high-speed scanning UV spectropho

TOTAL SYNTHESIS OF LIPOXINS A4 AND B4 FROM D-ISOASCORBIC ACID

A total convergent synthesis of lipoxins A4 and B4 has been carried out via four optically pure α-hydroxy and α,β-dihydroxyaldehydes, obtained from D-isoascorbic acid as a single starting material.Connection by a six carbons unit uses Wittig-type reaction

TOTAL SYNTHESIS OF LIPOXIN B: ASSIGNMENT OF STEREOCHEMISTRY

Four isomers of lipoxin B were synthesized using carbohydrate precursors.An authentic sample of lipoxin B (from human leukocytes) was found to be a mixture of all-trans isomers 1a and 1c.