Interferon Gamma-1b, also known as IFN-γ1b, is a recombinant DNA product that functions as an antineoplastic, biological response modifier, and immunoregulator. It has orphan drug status for the treatment of chronic granulomatous disease and is being investigated for its potential in treating trauma-related infections and atopic dermatitis.
Used in Pharmaceutical Industry:
INTERFERON GAMMA 1 B is used as an antineoplastic agent for its ability to inhibit the growth and proliferation of cancer cells, making it a valuable component in cancer treatment.
INTERFERON GAMMA 1 B is used as a biological response modifier to enhance the body's immune response, which can be beneficial in fighting infections and other diseases.
INTERFERON GAMMA 1 B is used as an immunoregulator to modulate the immune system, helping to maintain a balanced response and potentially treating conditions like chronic granulomatous disease, trauma-related infections, and atopic dermatitis.

98059-61-1

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Basic information
1. Product Name: INTERFERON GAMMA 1 B
2. Synonyms: INTERFERON GAMMA 1 B;Interferon γ-1b;Interferon γ-1b for system suitability;Interferon γ-1b validation solution
3. CAS NO:98059-61-1
4. Molecular Formula:
5. Molecular Weight: 0
6. EINECS: N/A
7. Product Categories: N/A
Chemical Properties
1. Melting Point: N/A
2. Boiling Point: N/A
3. Flash Point: N/A
4. Appearance: /
5. Density: N/A
6. Refractive Index: N/A
7. Storage Temp.: N/A
8. Solubility: N/A
9. CAS DataBase Reference: INTERFERON GAMMA 1 B(CAS DataBase Reference)
10. NIST Chemistry Reference: INTERFERON GAMMA 1 B(98059-61-1)
11. EPA Substance Registry System: INTERFERON GAMMA 1 B(98059-61-1)
Safety Data
1. Hazard Codes: N/A
2. Statements: N/A
3. Safety Statements: N/A
4. WGK Germany:
5. RTECS:
6. HazardClass: N/A
7. PackingGroup: N/A
8. Hazardous Substances Data: 98059-61-1(Hazardous Substances Data)

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98059-61-1 Usage

Clinical Use

Adjunct to antibiotics to reduce the frequency of serious infections in patients with chronic granulomatous disease

Drug interactions

Potentially hazardous interactions with other drugs Avoid with vaccines.

Metabolism

The metabolism of cloned interferons falls within the natural handling of proteins. Interferon gamma-1b was not detected in the urine of healthy male subjects following administration via IV, IM or SC routes. In vitro hepatic and renal perfusion studies demonstrate that the liver and kidneys are capable of clearing interferon gamma-1b from perfusate. Interferon is metabolised primarily in the kidney. It is excreted in the urine, but is reabsorbed by the tubules where it undergoes lysosomal degradation.

Check Digit Verification of cas no

The CAS Registry Mumber 98059-61-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,0,5 and 9 respectively; the second part has 2 digits, 6 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 98059-61:
(7*9)+(6*8)+(5*0)+(4*5)+(3*9)+(2*6)+(1*1)=171
171 % 10 = 1
So 98059-61-1 is a valid CAS Registry Number.

98059-61-1 Well-known Company Product Price

Brand
(Code)Product description
CAS number
Packaging
Price
Detail

Sigma-Aldrich
(I0320330) Interferon γ-1b European Pharmacopoeia (EP) Reference Standard
98059-61-1
I0320330-2EA
2,132.91CNY
Detail

Sigma-Aldrich
(Y0001664) Interferon γ-1b for system suitability European Pharmacopoeia (EP) Reference Standard
98059-61-1
Y0001664
1,880.19CNY
Detail

98059-61-1Upstream product

98059-61-1Downstream Products

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