98120-14-0Relevant articles and documents
AN EFFICIENT SYNTHESIS OF 3-AMINO-4-FLUOROBUTANOIC ACID, AN INACTIVATOR OF GABA TRANSAMINASE
Mathew, Jacob,Invergo, Benedict J.,Silverman, Richard B.
, p. 377 - 384 (2007/10/02)
3-Amino-4-fluorobutanoic acid (1), a potent in vivo-inactivator of GABA transaminase, is synthesized in two steps.The lithium salt of tert-butyl acetate is condensed with fluoroacetonitrile and the product is reduced with sodium cyanoborohydride in acidic methanol to 1.