98157-52-9

Usage

Structure

Pyrazolo-pyridine derivative with a nitro group and a methyl group attached to the heterocyclic ring

Potential biological activity

Particularly in the field of medicinal chemistry and drug development

Pharmacological properties

The structure suggests potential pharmacological properties

Building block

Could be used as a building block for the synthesis of novel compounds with therapeutic applications

Reactivity

Nitro and phenyl substitutions may contribute to its reactivity

Potential uses in organic chemistry reactions

Due to its reactivity and unique structure

Further research and testing

Necessary to fully understand and harness its potential in various scientific and industrial applications.

Upstream product

• 5653-21-4 metazonic acid 
• 52217-35-3 5-amino-3-methyl-1-phenyl-1H-pyrazole-4-carbaldehyde 
• 1131-18-6 1-Phenyl-3-methyl-5-aminopyrazole 
• 34461-00-2 nitromalondialdehyde sodium salt 

Downstream Products

• 1181669-30-6 3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridin-5-amine 
• 1016672-39-1 5-bromo-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 1418299-43-0 3-methyl-1-phenyl-5-p-tolyl-1H-pyrazolo[3,4-b]pyridine 
• 1418299-44-1 3-methyl-5-(3,5-dimethylphenyl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 1418299-45-2 5-(4-chlorophenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 1418299-46-3 5-(4-fluorophenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 
• 1418299-47-4 5-(4-(trifluoromethyl)phenyl)-3-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine 

Relevant academic research and scientific papers

Regioselective direct arylation of fused 3-nitropyridines and other nitro-substituted heteroarenes: The multipurpose nature of the nitro group as a directing group

We report Pd-and Ni-catalysed, guided and regioselective C-H arylations of a series of fused 3-nitropyridines. The method described here is a facile tool for the chemical functionalisation of drug-like fused pyridines. The scope and limitations of the rea

Design, synthesis and transformation of some heteroannulated 3-aminopyridines - Purine isosteres with exocyclic nitrogen atom

The synthesis of 1-deazapurines and isosteres bearing the exocyclic nitrogen atom at position-1 was developed basing on the formal [3+3]-cyclization reaction of nitro-malonaldehyde with the set of electron-excessive aminoheterocycles. Through the function

NITROAZINES. 20. SIMPLE SYNTHESES OF NITROPYRAZOLOPYRIDINES FROM ALIPHATIC NITROSYNTHONS AND AMINOPYRAZOLES

Two variants of a synthesis for nitropyrazolopyridines from aminopyrazoles and two- or three-carbon nitrosynthons are examined.