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5(6)-Carboxytetramethylrhodamine, also known as TAMRA or TMR, is a fluorescent dye that has gained prominence for its use in various applications, including oligonucleotide labeling and automated DNA sequencing. It is a mixed isomer of carboxytetramethylrhodamine free acid, which can be coupled to primary or secondary amines through standard peptide chemistry.

98181-63-6

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98181-63-6 Usage

Uses

Used in Biochemical Research:
5(6)-Carboxytetramethylrhodamine is used as a fluorescence probe for studying the distribution of molecules such as cell-penetrating peptides (CPPs). Its fluorescent properties allow researchers to track and visualize the behavior of these molecules within biological systems.
Used in Fluorescence-based Techniques:
TAMRA is utilized as a fluorescence partner in various applications, including two-dimensional fluorescence intensity distribution analysis (2D-FIDA), luminescence resonance energy transfer (LRET), and fluorescence resonance energy transfer (FRET). These techniques rely on the dye's ability to emit fluorescence upon excitation, enabling the investigation of molecular interactions and dynamics.
Used in Oligonucleotide Labeling and DNA Sequencing:
5(6)-Carboxytetramethylrhodamine is employed as a dye for labeling oligonucleotides and in automated DNA sequencing applications. Its fluorescent properties facilitate the detection and analysis of DNA sequences, contributing to advancements in genetic research and diagnostics.

Check Digit Verification of cas no

The CAS Registry Mumber 98181-63-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,1,8 and 1 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 98181-63:
(7*9)+(6*8)+(5*1)+(4*8)+(3*1)+(2*6)+(1*3)=166
166 % 10 = 6
So 98181-63-6 is a valid CAS Registry Number.
InChI:InChI=1/2C25H22N2O5.2ClH/c1-26(2)15-6-9-18-21(12-15)32-22-13-16(27(3)4)7-10-19(22)23(18)20-11-14(24(28)29)5-8-17(20)25(30)31;1-26(2)14-8-10-16-20(12-14)32-21-13-15(27(3)4)9-11-17(21)22(16)23-18(24(28)29)6-5-7-19(23)25(30)31;;/h2*5-13H,1-4H3,(H-,28,29,30,31);2*1H

98181-63-6 Well-known Company Product Price

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  • Sigma

  • (21953)  5(6)-Carboxytetramethylrhodamine  BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

  • 98181-63-6

  • 21953-100MG-F

  • 2,033.46CNY

  • Detail
  • Sigma

  • (21953)  5(6)-Carboxytetramethylrhodamine  BioReagent, suitable for fluorescence, ≥85% (sum of isomers, HPCE)

  • 98181-63-6

  • 21953-500MG-F

  • 6,961.50CNY

  • Detail

98181-63-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 11, 2017

Revision Date: Aug 11, 2017

1.Identification

1.1 GHS Product identifier

Product name [9-(2,5-dicarboxyphenyl)-6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium,[9-(2,6-dicarboxyphenyl)-6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium,dichloride

1.2 Other means of identification

Product number -
Other names 5(6)-Carboxytetramethylrhodamine hydrochloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:98181-63-6 SDS

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