98200-86-3Relevant academic research and scientific papers
Tosylhydrazine mediated conjugate reduction and sequential reductive coupling cyclization: Synthesis of 2-arylchromans
Shang, Xuyang,Zhou, Xiaomeng,Zhang, Wei,Wan, Changfeng,Chen, Junmin
supporting information, p. 8187 - 8193 (2015/12/30)
Tosylhydrazine mediated conjugate reduction of 2-hydroxyl chalcones and sequential reductive coupling cyclization is described. This is an unprecedented protocol and an extremely efficient method for a one-pot domino synthesis of 2-arylchromans in good to excellent yields from commercially available, cheap starting materials. More importantly, the two-step reactions can be easily controlled to afford dihydrochalcones or 2-arylchromans by the mole amounts of tosylhydrazine. Furthermore, the operational simplicity of the process and the high functional group tolerance are remarkable.
Transition metals catalyzed C-C and C-O bonds formation: Facile synthesis of flavans and benzoxepines
Ramulu, B. Venkat,Mahendar,Krishna,Reddy, A. Gopi Krishna,Suchand,Satyanarayana
, p. 8305 - 8315 (2013/09/02)
A simple and practical method has been developed based on intermolecular [Pd]-catalyzed C-C and an intramolecular [Cu]-catalyzed C-O bond formations for the synthesis of flavans and benzoxepines. Interestingly, the method is amenable for the synthesis of
An efficient intermolecular [Pd]-catalyzed C-C and intramolecular [Cu]-catalyzed C-O bonds formation: Synthesis of functionalized flavans and benzoxepine
Suchand,Krishna,Venkat Ramulu,Dibyendu,Gopi Krishna Reddy,Mahendar,Satyanarayana
, p. 3861 - 3864 (2012/08/14)
An efficient three-step strategy for the synthesis of functionalized flavans, starting from readily available 2-bromoiodobenzenes and aryl vinyl alcohols, is presented and successfully extended to benzoxepine. An intermolecular [Pd]-catalyzed C-C and an i
