98210-50-5

Basic information

• Product Name: L-Valine, N-[O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-L-seryl]-
• CAS NO: 98210-50-5
• Molecular Formula: C20H30N2O6
• Molecular Weight: 394.468
• Mol File: 98210-50-5.mol

Chemical Properties

• CAS DataBase Reference: L-Valine, N-[O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-L-seryl]-(CAS DataBase Reference)
• NIST Chemistry Reference: L-Valine, N-[O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-L-seryl]-(98210-50-5)
• EPA Substance Registry System: L-Valine, N-[O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-L-seryl]-(98210-50-5)

Safety Data

• Hazardous Substances Data: 98210-50-5(Hazardous Substances Data)

Upstream product

• 6306-52-1 L-valine methylester hydrochloride 
• 1676-75-1 N-benzyloxycarbonyl-O-t-butyl-L-serine 
• 177747-26-1 (S)-2-((S)-2-Benzyloxycarbonylamino-3-tert-butoxy-propionylamino)-3-methyl-butyric acid methyl ester 

Downstream Products

• 90983-18-9 Boc-Gly-Glu(OBu^t)-Phe-Ser(Bu^t)-Val-Cys(SBu^t)-Asp(OBu^t)-Ser(Bu^t)-OH 
• 98228-98-9 Boc-Gly-Glu(OBu^t)-Phe-Ser(Bu^t)-Val-Cys-Asp(OBu^t)-Ser(Bu^t)-OH 
• 90983-07-6 Boc-Gly-Glu(OBu^t)-Phe-Ser(Bu^t)-Val-OH 
• 98210-57-2 Z-Glu(OBu^t)-Phe-Ser(Bu^t)-Val-OH 
• 98210-58-3 H-Glu(OBu^t)-Phe-Ser(Bu^t)-Val-OH 
• 98210-55-0 Z-Phe-Ser(Bu^t)-Val-OH 
• 90983-01-0 Z-Val-Ser(Bu^t)-Val-OH 
• 98210-56-1 H-Phe-Ser(Bu^t)-Val-OH 
• 90983-02-1 Z-Val-Ser(Bu^t)-Val-Trp-Val-Gly-Asp(OBu^t)-Lys(Boc)-OBu^t 
• 177747-31-8 Z-Ser(t-Bu)-Val-Aib-Pro-Aib-Leu-Aib-Pro-Leuol 
• 177747-29-4 {(S)-2-tert-Butoxy-1-[(S)-1-(1,1-dimethyl-2-{(S)-2-[1-methyl-1-(methyl-phenyl-carbamoyl)-ethylcarbamoyl]-pyrrolidin-1-yl}-2-oxo-ethylcarbamoyl)-2-methyl-propylcarbamoyl]-ethyl}-carbamic acid benzyl ester 
• 177747-30-7 2-[((S)-1-{2-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-tert-butoxy-propionylamino)-3-methyl-butyrylamino]-2-methyl-propionyl}-pyrrolidine-2-carbonyl)-amino]-2-methyl-propionic acid 
• 177747-28-3 (S)-1-{2-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-tert-butoxy-propionylamino)-3-methyl-butyrylamino]-2-methyl-propionyl}-pyrrolidine-2-carboxylic acid 
• 177747-27-2 (S)-1-{2-[(S)-2-((S)-2-Benzyloxycarbonylamino-3-tert-butoxy-propionylamino)-3-methyl-butyrylamino]-2-methyl-propionyl}-pyrrolidine-2-carboxylic acid methyl ester 

Relevant articles and documents

A new 3-amino-2H-azirine as an Aib-Pro synthon: Synthesis of the C-terminal nonapeptide of trichovirin I 1B

The synthesis of methyl N-(2,2-dimethyl-2H-azirin-3-yl)-L-prolinate (3), a novel 3-amino-2H-azirine, is described. It is shown that the reaction of COCl2 with thioamide 5 is remarkably faster than with the corresponding amide 4, and the yield of 3 is much better in the synthesis starting with 5. The 3-amino-2H-azirine 3 has been used as a building block of the dipeptide moieties Aib-Pro in the synthesis of nonapeptide 17, the C-terminal 6-14 segment of the peptaibole trichovirin I 1B. The structure of 17 was established by single-crystal X-ray crystallography.