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"Z-Phe-Val-Lys(Boc)-OBut" is a peptide compound consisting of four amino acids: phenylalanine (Phe), valine (Val), and lysine (Lys), with the latter being protected by a tert-butyloxycarbonyl (Boc) group. The sequence is capped with a tert-butyl (OBut) group at the C-terminus. This specific arrangement and protection of the peptide are crucial for its stability and reactivity in chemical synthesis, particularly in solid-phase peptide synthesis (SPPS). The Boc group is a common protecting group for the amino group of lysine, which prevents unwanted side reactions during peptide bond formation. The OBut group at the end of the peptide chain serves to protect the carboxyl group and can be removed under acidic conditions to facilitate further elongation of the peptide chain. Z-Phe-Val-Lys(Boc)-OBut is a building block in the synthesis of larger peptides and proteins, and its protected nature allows for controlled and specific chemical reactions to occur.

98228-78-5

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98228-78-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 98228-78-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,2,2 and 8 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 98228-78:
(7*9)+(6*8)+(5*2)+(4*2)+(3*8)+(2*7)+(1*8)=175
175 % 10 = 5
So 98228-78-5 is a valid CAS Registry Number.

98228-78-5Relevant academic research and scientific papers

Synthesis of the Hypothetical Active Site of the Nerve Growth Factor

Wuensch, Erich

, p. 505 - 524 (2007/10/02)

The synthesis of an unsymmetrical cystine peptide corresponding to the sequence 10-25/75-88 of mouse nerve growth factor was performed via the newly developed sulfenohydrazide procedure.The triacontapeptide isolated at a high degree of purity after Sephadex-LH 20 chromatography, did not exhibit in the biological assays the expected nerve growth factor activity as reported by Revoltella and coworkers. - Keywords: Nerve growth factor; Peptide synthesis; Unsymmetrical cystine peptides

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