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"Z-Val-Gly-Asp(OBut)-Lys(Boc)-OBut" is a peptide compound consisting of five amino acids: Valine (Val), Glycine (Gly), Aspartic acid (Asp), and Lysine (Lys). The sequence is protected with a carbobenzoxy (Z) group at the N-terminus, a tert-butyl (OBut) group on the Asp side chain, and a Boc (tert-butoxycarbonyl) group on the Lys side chain. This specific arrangement and protection of the peptide are crucial for its stability and reactivity in chemical synthesis, particularly in solid-phase peptide synthesis, where the Boc and Z groups serve as protecting groups to prevent unwanted side reactions. The OBut groups on both the Asp side chain and the C-terminus further contribute to the peptide's stability during synthesis. Z-Val-Gly-Asp(OBut)-Lys(Boc)-OBut is a building block in the creation of larger peptides and proteins, with its specific sequence and protection scheme designed to facilitate controlled peptide bond formation and subsequent deprotection steps.

98229-44-8

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98229-44-8 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 98229-44-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,2,2 and 9 respectively; the second part has 2 digits, 4 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 98229-44:
(7*9)+(6*8)+(5*2)+(4*2)+(3*9)+(2*4)+(1*4)=168
168 % 10 = 8
So 98229-44-8 is a valid CAS Registry Number.

98229-44-8Relevant academic research and scientific papers

Synthesis of the Hypothetical Active Site of the Nerve Growth Factor

Wuensch, Erich

, p. 505 - 524 (2007/10/02)

The synthesis of an unsymmetrical cystine peptide corresponding to the sequence 10-25/75-88 of mouse nerve growth factor was performed via the newly developed sulfenohydrazide procedure.The triacontapeptide isolated at a high degree of purity after Sephadex-LH 20 chromatography, did not exhibit in the biological assays the expected nerve growth factor activity as reported by Revoltella and coworkers. - Keywords: Nerve growth factor; Peptide synthesis; Unsymmetrical cystine peptides

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