98231-55-1Relevant academic research and scientific papers
AN IMPROVED PROCESS FOR THE PREPARATION OF CHLORO METHYL CEPHEM DERIVATIVES
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Page 7; 10; 12, (2008/06/13)
The present invention provides an improved process to produce the chloromethylcephem derivatives of the formula (I), wherein R1 represents a carboxy-protecting group viz., substituted methyl group, which can be deprotected easily, such as t-butyl group, diphenylmethyl, 4-methoxybenzyl, 2-methoxybenzyl, 2-chlorobenzyl or benzyl group; R2 represents hydrogen, (C1-C4)alkyl, substituted or unsubstituted phenyl or substituted or unsubstituted phenoxy group.
