98269-22-8Relevant articles and documents
Preparation method of Na molecular fluorescent intermediate and preparation method of Na molecular fluorescent sensor
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Paragraph 0098; 0109-0111; 0160-0164, (2019/01/04)
The invention provides a preparation method of a Na molecular fluorescent intermediate and a preparation method of a Na molecular fluorescent sensor. The Na molecular fluorescent intermediatehas a structure as shown in a formula I. The preparation method of the Na molecular fluorescent intermediate comprises the following steps: S1, carrying out a substitution reaction on o-anisidineand alpha-methyl haloacetate to obtain a compound 2; S2, carrying out a reduction reaction on the compound 2 to obtain a compound 3; S3, carrying out a hydroxyl substitution on the compound 4 by adopting toluene sulfonyl chloride to obtain a compound 5, wherein the compound 4 has a structural formula as the follows; S4, carrying out a cyclization reaction on the compound 3 and the compound 5 to obtain a compound 6; S5, carrying out a formylation reaction on the compound 6 to obtain a compound 7; S6, carrying out a henry reaction on the compound 7 with nitromethane to obtain a compound 8; and S7, carrying out nitroso reduction reaction on the compound 8 to obtain the Na molecular fluorescent intermediate. The method is beneficial to improving the yield of the Na molecular fluorescentintermediate.
Sodium-Selective Fluoroionophore-Based Optodes for Seawater Salinity Measurement
Müller, Bernhard J.,Rappitsch, Tanja,Staudinger, Christoph,Rüschitz, Christian,Borisov, Sergey M.,Klimant, Ingo
, p. 7195 - 7202 (2017/07/22)
A new fluorescent sensor for Na+ is presented. The sensor relies on a Na+ selective fluoroionophore based on a bright red-emitting BODIPY chromophore. The fluorescence of the fluoroionophore is enhanced upon binding of Na+-ions to the highly selective aza-crown ether receptor due to reduction of the photoinduced electron transfer (PET) quenching. Solid state sensing materials were prepared by physically embedding the fluoroionophore into water-swellable biocompatible polymer matrices (polyurethane hydrogels), thus enabling continuous measurements of aqueous samples. Despite the simple design, the sensor showed no leaching of the indicator and featured fast and reversible response. Among different polyurethane hydrogels investigated, the hydrogel D1 featuring the highest water uptake was found to be the most suitable due to the highest dynamics between "off" and "on" states. Due to little or no cross sensitivity to other ions (e.g., Mg2+, Ca2+, K+) and its insensitivity to potential changes in pH, this sensor is promising for use in clinical diagnostics and for biological and marine applications. Fiber-optic sensors based on referenced read-out with a compact phase fluorimeter were prepared. To demonstrate their practical applicability, the sensors were used to determine the salinity in the seawater and brackish water of the Baltic Sea.
A fluorescent combinatorial logic gate with Na+, H+-enabled or and H+-driven low-medium-high ternary logic functions
Spiteri, Jasmine M. A.,Mallia, Carl J.,Scerri, Glenn J.,Magri, David C.
, p. 10116 - 10121 (2017/12/26)
A novel fluorescent molecular logic gate with a 'fluorophore-spacer1-receptor1-spacer2-receptor2' format is demonstrated in 1:1 (v/v) methanol/water. The molecule consists of an anthracene fluorophore, and terti
A fluorescent chemosensor for sodium based on photoinduced electron transfer
He, Huarui,Mortellaro, Mark A.,Leiner, Marc J. P.,Young, Susanne T.,Fraatz, Robert J.,Tusa, James K.
, p. 549 - 555 (2007/10/03)
A new optical sensor suitable for practical measurement of sodium in serum and whole blood samples is described. The optical sensor is based on a novel PET (photoinduced eletron transfer) fluoroionophore immobilized in a hydrophilic polymer layer. The des
A novel optically based chemosensor for the detection of blood Na+
Gunnlaugsson, Thorfinnur,Nieuwenhuyzen, Mark,Richard, Ludovic,Thoss, Vera
, p. 4725 - 4728 (2007/10/03)
The azo dye based chemosensor 2 displays extremely good sensitivity and selectivity for Na+ over other physiologically important alkali and alkali earth metal ions in the 0.3-1.0×10-4 M concentration range as well as being pH independent above pH 3.9. This sensitivity coincides with the Na+ concentration range found in blood. The sensor exhibits almost 110 nm hypsochromic shift in the absorption spectrum upon Na+ detection, with a strong colour change from red to yellow in aqueous solution which is clearly visible to the naked eye even at low concentrations.
Efficient synthesis of N-Aryl-aza-crown ethers via palladium-catalyzed amination
Zhang,Buchwald
, p. 8027 - 8031 (2007/10/03)
N-Aryl-aza-crown ethers were efficiently prepared by reaction of an aza-crown ether with an aryl bromide via a palladium-catalyzed amination. The combination of Pd2(dba)3 and a biphenyl-based electron-rich bulky monophosphine is effective for catalyzing the coupling of 1-aza-15-crown-5 with both electron-deficient and electron-rich aryl bromides under mild conditions. N-Aryl-aza-crown ethers were produced in 75-91% yields. N-Aryl-aza-crown ethers with o-aryl substituents can also be synthesized using this catalyst system, albeit in lower yields (~40%).
