98349-72-5Relevant academic research and scientific papers
Internal energy deposition for low energy, femtosecond laser vaporization and nanospray post-ionization mass spectrometry using thermometer ions
Flanigan, Paul M.,Shi, Fengjian,Archer, Jieutonne J.,Levis, Robert J.
, p. 716 - 724 (2015)
The internal energy of p-substituted benzylpyridinium ions after laser vaporization using low energy, femtosecond duration laser pulses of wavelengths 800 and 1042 nm was determined using the survival yield method. Laser vaporization of dried benzylpyridi
Weakly coordinating group directed rhodium-catalyzed unconventional site-selective C–H olefination of indolizines at the 8-position
Feng, Xue,Tian, Jiaxin,Sun, Ying,Hu, Huayou,Lu, Mingzhu,Kan, Yuhe,Fang, Danjun,Wang, Chao
supporting information, p. 470 - 474 (2020/03/19)
A rhodium-catalyzed directing group promoted selective C–H olefination reaction of indolizines at the 8-position is reported. Di-olefination at 2,8-positions also achieved with silver hexafluoroantimonate as an additive under similar reaction conditions. Weakly coordinating groups, such as ketone, aldehyde, amide and ester, were used as directing groups. The ester group can be removed under acid conditions and therefore is used as a traceless directing group.
Application of primary halogenated hydrocarbons for the synthesis of 3-Aryl and 3-Alkyl indolizines
Liu, Yan,Hu, Huayou,Zhou, Junyu,Wang, Wenhui,He, Youliang,Wang, Chao
, p. 5016 - 5024 (2017/07/10)
Indolizine is an important heterocyclic compound with several interesting properties that make it suitable for numerous applications in many fields, such as biology, medicine and materials. However, the synthesis of 3-Alkyl indolizines from bulky primary halogenated alkanes has not yet been reported. Herein, a transition-metal-free synthetic route to 3-Aryl and 3-Alkyl indolizines from electron-deficient alkenes, pyridines and primary halogenated hydrocarbons has been reported for the first time using a tandem reaction. The key step of this method is the oxidative dehydrogenative aromatization of a tetrahydroindolizine intermediate with 2,2,6,6-Tetramethylpiperidine-N-oxyl (TEMPO) as the oxidant. The advantages of this protocol are its use of easily available and low-cost starting materials, the transition-metal-free conditions and its ready scalability.
Determination of internal energy distributions of laser electrospray mass spectrometry using thermometer ions and other biomolecules
Flanigan, Paul M.,Shi, Fengjian,Perez, Johnny J.,Karki, Santosh,Pfeiffer, Conrad,Schafmeister, Christian,Levis, Robert J.
, p. 1572 - 1582 (2014/08/18)
(Figure Presented) The internal energy distributions for dried and liquid samples that were vaporized with femtosecond duration laser pulses centered at 800 nm and postionized by electrospray ionization-mass spectrometry (LEMS) were measured and compared
Surface acoustic wave nebulization produces ions with lower internal energy than electrospray ionization
Huang, Yue,Turecek, Frantisek,Yoon, Sung Hwan,Heron, Scott R.,Masselon, Christophe D.,Edgar, J. Scott,Goodlett, David R.
, p. 1062 - 1070,9 (2020/08/24)
Surface acoustic wave nebulization (SAWN) has recently been reported as a novel method to transfer non-volatile analytes directly from solution to the gas phase for mass spectrometric analysis. Here we present a comparison of the survival yield of SAWN ve
Non-thermal internal energy distribution of ions observed in an electrospray source interfaced with a sector mass spectrometer
Rondeau, David,Galland, Nicolas,Zins, Emilie-Laure,Pepe, Claude,Drahos, Laszlo,Vekey, Karoly
experimental part, p. 100 - 111 (2011/10/05)
The internal energy distribution P(Eint) of ions emitted in an electrospray (ESI) source interfaced with a sector mass spectrometer is evaluated by using the experimental survival yield (SY) method including the kinetic shift. This method is ba
A one-pot domino reaction for the synthesis of 3-arylindolizines from pyridines, benzyl halides, and dihalide-substituted electron-deficient alkenes
Hu, Huayou,Shi, Kunbo,Hou, Rongrong,Zhang, Zaichao,Zhu, Yulan,Zhou, Jianfeng
experimental part, p. 4007 - 4014 (2011/02/22)
3-Arylindolizines were prepared by one-pot domino reactions from benzyl halides with pyridine (or isoquinoline) and cyclic or acyclic dihalide-substituted electron-deficient alkenes in the presence of potassium carbonate via in situ generated N-ylide intermediate. Both electron-donating and electron-withdrawing groups are tolerated in the aryl ring of benzyl halides. The yields range from moderate to high. Georg Thieme Verlag Stuttgart - New York.
