98351-91-8Relevant academic research and scientific papers
Distinctive reactivity of N-benzylidene-[1,1'-biphenyl]-2-amines under photoredox conditions
Cho, Eun Jin,Iqbal, Naeem,Min, Kwan Hong,Tambe, Shrikant D.
supporting information, p. 1335 - 1342 (2020/07/10)
A simple photocatalytic method was developed for the synthesis of unsymmetrical 1,2-diamines by the unprecedented reductive coupling of N-benzylidene-[1,1'-biphenyl]-2-amines with an aliphatic amine. The presence of a phenyl substituent in the aniline moiety of the substrate was critical for the reactivity. The reaction proceeded via radical–radical cross-coupling of α-amino radicals generated by proton-coupled single-electron transfer in the presence of an Ir photocatalyst. On the other hand, symmetrical 1,2-di-amines were selectively produced from the same starting materials by the judicious choice of the reaction conditions, showcasing the distinct reactivity of N-benzylidene-[1,1'-biphenyl]-2-amines. The developed method can be employed for the synthesis of various bulky vicinal diamines, which are potential ligands in stereoselective synthesis.
Palladium and radical routes to phenanthridines
Bowman, W. Russell,Lyon, Jessica E.,Pritchard, Gareth J.
, p. 210 - 227 (2013/01/16)
Two routes to phenanthridines are reported; a palladium-mediated route using imidoyl-selanides as precursors and a modified radical route using aryl imines as starting materials. ARKAT-USA, Inc.
