98361-99-0

Upstream product

• 501-53-1 benzyl chloroformate 
• 98362-05-1 (R)-((4S,5R)-5-Aminomethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methanol 
• 35023-80-4 2,3:5,6-di-O-isopropylidene-D-mannose oxime 

Downstream Products

• 98362-02-8 3-{(2R,3S)-3-[(4R,5R)-5-(Benzyloxycarbonylamino-methyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranyl}-propionic acid ethyl ester 
• 98393-47-6 (E)-3-{(2R,3S)-3-[(4R,5R)-5-(Benzyloxycarbonylamino-methyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranyl}-acrylic acid ethyl ester 
• 98362-01-7 [(4R,5R)-5-((2S,3R)-3-Hydroxymethyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-carbamic acid benzyl ester 
• 98393-46-5 [(4R,5R)-5-((2R,3S)-3-Formyl-oxiranyl)-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl]-carbamic acid benzyl ester 
• 85624-09-5 (3aR,9R,9aR,9bS)-octahydro-2,2-dimethyl-[1,3]dioxolo[4,5-a]indolizin-9-ol 
• 72741-87-8 swainsonine 
• 98362-00-6 Methanesulfonic acid (R)-[(4R,5R)-5-(benzyloxycarbonylamino-methyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-((R)-2,2-dimethyl-[1,3]dioxolan-4-yl)-methyl ester 

Relevant academic research and scientific papers

Enantiospecific Total Synthesis of (-)-Swainsonine: New Aplications of Sodium Borohydride Reduction

A short, enantiospecific synthesis of (-)-swainsonine (1) from D-mannose has been achieved by a route involving, as a key step, a double cyclization of 4c.The synthesis takes adventage of new features of sodium borohydride for reducing conjugated esters and lactams.