98377-75-4Relevant academic research and scientific papers
Synthesis and fungicidal activity of 1-(alpha-tert-butylcinnamoyl)imidazoles.
Manabe, Akio,Takano, Hirotaka,Furuzawa, Kunihiko,Yanagi, Kazunori,Hisada, Yoshio,Tanaka, Shizuya
, p. 2243 - 2246 (2007/10/03)
Several 1-(alpha-tert-butylcinnamoyl)imidazoles were prepared to examine their fungicidal activity. The (Z)-4-chlorocinnamoyl derivative was prepared from (anti)-2-tert-butyl-3-(4-chlorophenyl)-3-hydroxypropanoic acid by treating with 1,1'-carbonyldiimidazole and a subsequent beta-elimination reaction at an elevated temperature. The (Z)-isomer of the 4-chlorocinnamoyl derivative showed good fungicidal activity against Erysiphe graminis and Botrytis cinerea in pot tests, whereas the corresponding (E)-isomer derived from the (Z)-isomer through photoisomerization was much less active.
