98421-40-0

Basic information

• Product Name: 2,2,2-Trifluoro-1-((R)-2-phenyl-pyrrolidin-1-yl)-ethanone
• Synonyms: 2,2,2-Trifluoro-1-((R)-2-phenyl-pyrrolidin-1-yl)-ethanone
• CAS NO: 98421-40-0
• Molecular Weight: 243.229
• Mol File: 98421-40-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2,2,2-Trifluoro-1-((R)-2-phenyl-pyrrolidin-1-yl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2,2-Trifluoro-1-((R)-2-phenyl-pyrrolidin-1-yl)-ethanone(98421-40-0)
• EPA Substance Registry System: 2,2,2-Trifluoro-1-((R)-2-phenyl-pyrrolidin-1-yl)-ethanone(98421-40-0)

Safety Data

• Hazardous Substances Data: 98421-40-0(Hazardous Substances Data)

Upstream product

• 116437-41-3 tert-butyl (4-oxo-4-phenyl-butyl)-carbamate 
• 407-25-0 trifluoroacetic anhydride 

Relevant articles and documents

Enantioselective Synthesis of 2-Substituted Pyrrolidines via Intramolecular Reductive Amination

Catalyzed by the complex generated in situ from iridium and the chiral ferrocene ligand, tert -butyl (4-oxo-4-arylbutyl)carbamate substrates were deprotected and then reductively cyclised to form 2-substituted arylpyrrolidines in a one-pot manner, in which the intramolecular reductive amination was the key step. A range of chiral 2-substituted arylpyrrolidines were synthesised in up to 98percent yield and 92percent ee.