98426-48-3 Usage
Biochem/physiol Actions
N-Butyryl-DL-homoserine lactone is a member of N-acyl-homoserine lactone family. N-acylhomoserine lactones (AHL) regulate gene expression in gram-negative bacteria, such as Echerichia and Salmonella are involved in quorum sensing, cell to cell communication among bacteria. Some AHLs are potent chemoattractants for human immune cells such as neutrophils.
Check Digit Verification of cas no
The CAS Registry Mumber 98426-48-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,8,4,2 and 6 respectively; the second part has 2 digits, 4 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 98426-48:
(7*9)+(6*8)+(5*4)+(4*2)+(3*6)+(2*4)+(1*8)=173
173 % 10 = 3
So 98426-48-3 is a valid CAS Registry Number.
98426-48-3Relevant academic research and scientific papers
ACYL HOMOSERINE LACTONES FOR INHIBITION OF CELL GROWTH
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Page/Page column 9-10, (2008/06/13)
The present invention provides a method for inhibiting the growth of cancer cells using AHLs of the general formula CX-homoserine lactone where "X" represents a number of between 5 and 14 carbon atoms in the acyl chain of the AHL. The method comprises the step of administering to an individual an amount of an AHL effective to inhibit the growth of cancer cells. Also provided is a method for enhancing the effect of a chemotherapeutic agent comprising the step of administering to an individual the chemotherapeutic agent and an amount of an AHL effective to enhance the cancer cell growth inhibitory effect of the chemotherapeutic agent.
