98450-35-2Relevant academic research and scientific papers
Heterocycles from α-Nitroolefins, IX. - N-Substituted 3-Pyrrolecarboxylates from 4,5-Dihydro-5-(methyleneamino)-3-furancarboxylates
Boberg, Friedrich,Garburg, Karl-Heinz,Garming, Alfons,Goerlich, Karl-Joachim,Pipereit, Eberhard,Ruhr, Maria
, p. 1119 - 1135 (2007/10/02)
Catalytic hydrogenation of 4,5-dihydro-5-(methyleneamino)-3-furancarboxylates 1 yields N-substituted pyrroles 6a-u with enolizable rests at nitrogen and 6v-y with non-enolizable rests at nitrogen.The N-substituted pyrroles 6, 7 react with sodium hypochlorite at the rests standing at nitrogen to yield chlorination products 8.O-Methylated products 9 have been prepared from several N-substituted pyrroles 6 and their enoles 7 with diazomethane; the N-substituted pyrrole 6x yields the C-methylated product 10x.
